… Two 14-3-3 subunits associate strongly with each other to form saddle- or C-shaped
dimers. … , while the C-terminal helices form its walls [17,18]. In some 14-3-3 isoforms, a C-terminal …

A major change in recent years has been the recognition that severe malaria, predominantly
caused by Plasmodium falciparum, is a complex multi-system disorder presenting with a …

… 5C). The frequency of mutations is also much higher for PRKAA2 than PRKAA1, although
the proportions of missense mutations are quite similar (Figs 3C and 4C). Thus, amplification …

… 150C was essential to obtain complete peptide bond cleavage. Microcystin-LR was diluted in
50 mM Tris-HCl, pH 7.0 (4C) … catalytic subunits (RW MacKintosh, personal communication). …

Background The safety, effectiveness, and cost-effectiveness of molnupiravir, an oral
antiviral medication for SARS-CoV-2, has not been established in vaccinated patients in the …

… and incubatedfor 2 min at 4 C; the reaction was started by the addition of [32P] phosphorylase
a, and the mixture was incubated for 10 min at 30 C. Two hundred microliters of 20% …

BACKGROUND: Reduced bone mineral density in patients with inflammatory bowel disease
is thought to be due to disturbances in calcium homeostasis or the effects of corticosteroid …

… binding with high affinity to poly(C) sequences in RNA, and whose roles include regulating
the stability of mRNA and the efficiency of its translation; namely poly(C)-binding protein, an …

… The transfectants were exposed to heat shock followed by 6 h recovery at 37C (R) or were
left untreated (C). Mock, cells cotransfected with an empty vector and the reporter plasmid. (A) …

… temperature (20 C) for 1 h. Lysate (3 mg) was then added and mixed for a further 2 h at 4
C. Cells … additions and corrections for Supplementary Table 1 to c.mackintosh@dundee.ac.uk. …