Care bundles can be a powerful driver for improving the reliability of delivery of evidence-
based care and patient outcomes. It remains to be seen whether the success that has been …

We performed a multicentre retrospective cohort study including 606,649 acute inpatient
episodes at 10 European hospitals in 2010 and 2011 to estimate the impact of antimicrobial …

Background: Despite improvements in management, infective endocarditis remains
associated with high mortality and morbidity. We describe temporal changes in the incidence, …

Study question What is the predicted risk of acute kidney injury after orthopaedic surgery
and does it affect short term and long term survival? Methods The cohort comprised adults …

In 2009, the Scottish government issued a target to reduce Clostridium difficile infection by
30% in 2 years. Consequently, Scottish hospitals changed from cephalosporins to gentamicin …

Background Skin and soft tissue infections (SSTIs) are caused by bacterial invasion of the
skin and underlying soft tissues and can present with a wide spectrum of signs, symptoms and …

There is strong evidence that self-monitoring and feedback are effective behaviour change
techniques (BCTs) across a range of healthcare interventions and that their effectiveness is …

Scope Antibiotic stewardship programmes (ASPs) are necessary in hospitals to improve the
judicious use of antibiotics. While ASPs require complex change of key behaviours on …

The increasing clinical importance of human infections (frequently severe) caused by Clostridium
difficile PCR ribotype 078 (RT078) was first reported in 2008. The severity of symptoms …

Background: hospital-acquired pneumonia poses a hazard to older people who are hospitalised,
yet few data exist on the incidence or risk factors in non-intensive care patients. This …