[HTML][HTML] SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness

…, AT DiPiazza, KH Dinnon, SM Elbashir, CA Shaw… - Nature, 2020 - nature.com
A vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is needed to
control the coronavirus disease 2019 (COVID-19) global pandemic. Structural studies have …

Chromosomal instability drives metastasis through a cytosolic DNA response

…, TBK Watkins, NK Taunk, M Duran, C Pauli, C Shaw… - Nature, 2018 - nature.com
Chromosomal instability is a hallmark of cancer that results from ongoing errors in chromosome
segregation during mitosis. Although chromosomal instability is a major driver of tumour …

ICIQ: a brief and robust measure for evaluating the symptoms and impact of urinary incontinence

K Avery, J Donovan, TJ Peters, C Shaw… - … : Official Journal of …, 2004 - Wiley Online Library
Aims To develop and evaluate the International Consultation on Incontinence Questionnaire
(ICIQ), a new questionnaire to assess urinary incontinence and its impact on quality of life (…

Nonviral delivery of self-amplifying RNA vaccines

…, A Verma, GR Otten, CA Shaw… - Proceedings of the …, 2012 - National Acad Sciences
Despite more than two decades of research and development on nucleic acid vaccines, there
is still no commercial product for human use. Taking advantage of the recent innovations …

Implications of human genome architecture for rearrangement-based disorders: the genomic basis of disease

CJ Shaw, JR Lupski - Human molecular genetics, 2004 - academic.oup.com
The term ‘genomic disorder’ refers to a disease that is caused by an alteration of the
genome that results in complete loss, gain or disruption of the structural integrity of a dosage …

Spiritual well-being, religiosity, hope, depression, and other mood states in elderly people coping with cancer.

RJ Fehring, JF Miller, C Shaw - Oncology nursing forum, 1997 - europepmc.org
Methods Each subject was administered an intrinsic and extrinsic religiosity index, a spiritual
well-being scale, a geriatric depression scale, the Miller hope scale, and the Profile of Mood …

Exploratory randomised controlled trial of a mindfulness-based weight loss intervention for women

K Tapper, C Shaw, J Ilsley, AJ Hill, FW Bond, L Moore - Appetite, 2009 - Elsevier
To explore the efficacy of a mindfulness-based weight loss intervention for women. Sixty-two
women (ages 19–64; BMI 22.5–52.1) who were attempting to lose weight were randomised …

Efficacy and safety of an mRNA-based RSV Pref vaccine in older adults

…, K Slobod, SK Stoszek, CA Shaw… - … England Journal of …, 2023 - Mass Medical Soc
Background Respiratory syncytial virus (RSV) can cause substantial morbidity and mortality
among older adults. An mRNA-based RSV vaccine, mRNA-1345, encoding the stabilized …

Concept maps: A strategy to teach and evaluate critical thinking

BJ Daley, CA Shaw, T Balistrieri… - Journal of nursing …, 1999 - journals.healio.com
The purpose of this article is to describe a study that implemented concept maps as a
methodology to teach and evaluate critical thinking. Students in six senior clinical groups were …

[HTML][HTML] A cationic nanoemulsion for the delivery of next-generation RNA vaccines

LA Brito, M Chan, CA Shaw, A Hekele, T Carsillo… - Molecular Therapy, 2014 - cell.com
Nucleic acid-based vaccines such as viral vectors, plasmid DNA, and mRNA are being
developed as a means to address a number of unmet medical needs that current vaccine …