… Buckley and coworkers have measured pharmacokinetic parameters in the breast (31)
and prostate (32). Henderson and coworkers measured F , PS , and vb in canine mammary …

Background: Health care workers (HCWs) are at risk for severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection. Purpose: To examine the burden of SARS-CoV-2, …

Imaging biomarkers (IBs) are integral to the routine management of patients with cancer. IBs
used daily in oncology include clinical TNM stage, objective response and left ventricular …

In many human infections, hosts and pathogens coexist for years or decades. Important
examples include HIV, herpes viruses, tuberculosis, leprosy, and malaria. With the exception of …

Background Cerebral sinovenous thrombosis in children is a serious disorder, and information
is needed about its prevention and treatment. Methods The Canadian Pediatric Ischemic …

… (D) Crystal structure of dBET1 bound to BRD4 bromodomain 1 (E) Docking of (D) into the
published DDB1-CRBN structure (F) dBET1-induced ternary complex formation of recombinant …

Background. The adverse effects of alcohol on the developing human represent a spectrum
of structural anomalies and behavioral and neurocognitive disabilities, most accurately …

The current predominant therapeutic paradigm is based on maximizing drug-receptor
occupancy to achieve clinical benefit. This strategy, however, generally requires excessive drug …

Lipid oxidation is one of the primary mechanisms of quality deterioration in foods and especially
in meat products. The changes in quality are manifested by adverse changes in flavor, …

Lipid oxidation is one of the main factors limiting the quality and acceptability of meats and
meat products. Oxidative damage to lipids occurs in the living animal because of an …