Mechanisms of bronchial hyperreactivity in asthma and chronic obstructive pulmonary disease

DC Grootendorst, KF Rabe - Proceedings of the American Thoracic …, 2004 - atsjournals.org
Bronchial hyperreactivity has long been recognized as a hallmark of chronic asthma. Less
is known about the prevalence and mechanisms of hyperreactivity in chronic obstructive …

Cardiovascular and noncardiovascular mortality among patients starting dialysis

DJ de Jager, DC Grootendorst, KJ Jager, PC van Dijk… - Jama, 2009 - jamanetwork.com
Context Cardiovascular mortality is considered the main cause of death in patients receiving
dialysis and is 10 to 20 times higher in such patients than in the general population. …

Performance of the Cockcroft-Gault, MDRD, and new CKD-EPI formulas in relation to GFR, age, and body size

WM Michels, DC Grootendorst, M Verduijn… - Clinical Journal of the …, 2010 - journals.lww.com
Background and objectives: We compared the estimations of Cockcroft-Gault, Modification of
Diet in Renal Disease (MDRD), and Chronic Kidney Disease Epidemiology Collaboration (…

Screening strategies for chronic kidney disease in the general population: follow-up of cross sectional health survey

SI Hallan, K Dahl, CM Oien, DC Grootendorst… - Bmj, 2006 - bmj.com
Objective To find an effective screening strategy for detecting patients with chronic kidney
disease and to describe the natural course of the disease. Design Eight year follow-up of a …

High plasma phosphate as a risk factor for decline in renal function and mortality in pre-dialysis patients

…, M Noordzij, DC Grootendorst… - Nephrology Dialysis …, 2007 - academic.oup.com
Background. Hyperphosphataemia is associated with increased mortality in patients with
chronic kidney disease (CKD) stage IV or on dialysis. Furthermore, in animal studies, elevated …

Clinical applications of assessment of airway inflammation using induced sputum

…, EH Bel, I Pin, DC Grootendorst… - European …, 2002 - Eur Respiratory Soc
Airway diseases account for a significant proportion of the respiratory physician! s workload.
Traditionally, conditions are classified according to clinical symptoms and abnormalities of …

Chronic sinusitis in severe asthma is related to sputum eosinophilia

A ten Brinke, DC Grootendorst, JT Schmidt… - Journal of Allergy and …, 2002 - Elsevier
Background: Chronic rhinosinusitis and asthma are conditions that frequently coexist,
particularly in severe asthma. The precise mechanism of the relationship between upper and …

Reduction in sputum neutrophil and eosinophil numbers by the PDE4 inhibitor roflumilast in patients with COPD

DC Grootendorst, SA Gauw, RM Verhoosel, PJ Sterk… - Thorax, 2007 - thorax.bmj.com
Background: Roflumilast is a targeted oral once-daily administered phosphodiesterase 4 (PDE4)
inhibitor with clinical efficacy in chronic obstructive pulmonary disease (COPD). Results …

Association between serum albumin and mortality in dialysis patients is partly explained by inflammation, and not by malnutrition

R de Mutsert, DC Grootendorst, F Indemans… - Journal of renal …, 2009 - Elsevier
OBJECTIVE: We investigated the effects of inflammatory and nutritional status on the association
between serum albumin and mortality in hemodialysis (HD) and peritoneal dialysis (PD…

[HTML][HTML] Subjective global assessment of nutritional status is strongly associated with mortality in chronic dialysis patients

R de Mutsert, DC Grootendorst, EW Boeschoten… - The American journal of …, 2009 - Elsevier
Background: The subjective global assessment of nutritional status (SGA) is used to assess
the nutritional status of chronic dialysis patients, but longitudinal data in relation to mortality …