Prevention of necrotising enteritis in Papua New Guinea by active immunisation

G Lawrence, F Shann, DS Freestone, PD Walker - The Lancet, 1979 - Elsevier
Necrotising enteritis (pig-bel) caused by Clostridium welchii type C is a major cause of
illness and death in the Highlands of Papua New Guinea. In a controlled trial of active …

Intranasal Lymphoblastoid Interferon (" Well fer on") Prophylaxis Against Rhinovirus and Influenza Virus in Volunteers

…, JS Willman, DAJ Tyrrell, DS Freestone… - Journal of interferon …, 1984 - liebertpub.com
Purified lymphoblastoid interferon (HuIFN-α) or placebo was self-administered intranasally
by volunteers using a spray device three times daily for four and one-third days beginning …

The need for new antiviral agents

DS Freestone - Antiviral research, 1985 - Elsevier
Population density and immune status, vectors and virulence of infection, nutritional status,
sanitation, genetic susceptibility and medical management of cases, are important factors …

Stabilized 17D strain yellow fever vaccine: dose response studies, clinical reactions and effects on hepatic function

DS Freestone, RD Ferris, AL Weinberg… - Journal of biological …, 1977 - Elsevier
Neutralizing antibody responses and clinical reactions were similar in groups of volunteers
vaccinated subcutaneously with doses of 10 5·3 pfu (10 4·2–4·4 mouse LD 50 units) of either …

Failure of oral 4′, 6-dichloroflavan to protect against rhinovirus infection in man

RJ Phillpotts, J Wallace, DAJ Tyrrell, DS Freestone… - Archives of …, 1983 - Springer
4′, 6-Dichloroflavan, a potent inhibitor of rhinovirus replicationin vitro, was tested in a
double-blind placebo controlled volunteer trial for its protective effect against experimental …

Antibody responses and resistance to challenge in volunteers vaccinated with live attenuated, detergent split and oil adjuvant A2/Hong Kong/68 (H3N2) influenza …

DS Freestone, S Hamilton-Smith, GC Schild… - Epidemiology & …, 1972 - cambridge.org
Forty-nine subjects were vaccinated with either live attenuated, detergent split, or oil adjuvant
A2/Hong Kong influenza vaccines, or a saline influenza B vaccine as control. Respiratory …

Vaccination of adults with Wistar RA 27/3 rubella vaccine

DS Freestone, J Prydie, SGH Smith… - Epidemiology & …, 1971 - cambridge.org
DS FREESTONE AND OTHEES careful explanation of the hazards of vaccination in pregnancy
was given and a pre-vaccination pregnancy test was also performed. Nevertheless it is …

Failure of intranasally administered 4′, 6-dichloroflavan to protect against rhinovirus infection in man

…, DAJ Tyrrell, WM Shepherd, DS Freestone - Archives of …, 1987 - Springer
4′,6-Dichloroflavan, a potent inhibitor of rhinovirus replication in tissue culture systems was
tested in a double-blind, placebo-controlled volunteer trial for its protective efficacy against …

Vaccination of schoolgirls against rubella. Assessment of serological status and a comparative trial of Wistar RA 27/3 and Cendehill strain live attenuated rubella …

DS Freestone, GM Reynolds, JA McKinnon… - … of Epidemiology & …, 1975 - jech.bmj.com
A total of 1525 schoolgirls aged 13 years from 21 schools in the County Borough of Dudley,
were bled for titration of rubella haemagglutinating inhibiting antibody and then were …

Recombinant WRL 105 strain live attenuated influenza vaccine: immunogenicity, reactivity, and transmissibility

CA Morris, VM Stealey, DS Freestone, PR Oliver - The Lancet, 1975 - Elsevier
The immunogenicity, reactivity, and transmissibility of recombinant WRL 105 (H3N2) (A/Okuda/57
× A/Finland/4/74) strain live attenuated influenza virus vaccine were studied in adult …