… HE account here published of the explorations of David Thompson in the western parts of
Canada and the United States was written by Thompson himself when he was about seventy …

PURPOSE: To review the effectiveness of exercise-based cardiac rehabilitation in patients
with coronary heart disease. METHODS: A systematic review and meta-analysis of …

Railways are an environmentally friendly means of transport well suited to modern society.
However, noise and vibration are key obstacles to further development of the railway …

The authors exploit the remarkable similarity between recent climate trends and the structure
of the ‘‘annular modes’’in the month-to-month variability (as described in a companion …

The leading empirical orthogonal function of the wintertime sea‐level pressure field is more
strongly coupled to surface air temperature fluctuations over the Eurasian continent than the …

The leading modes of variability of the extratropical circulation in both hemispheres are
characterized by deep, zonally symmetric or ‘‘annular’’structures, with geopotential height …

Chronic neuropathic pain, caused by lesions in the peripheral or central nervous system,
comes in many forms. We describe current approaches to the diagnosis and assessment of …

Background Coronary heart disease (CHD) is the single most common cause of death globally.
However, with falling CHD mortality rates, an increasing number of people live with CHD …

Climate variability in the high-latitude Southern Hemisphere (SH) is dominated by the SH
annular mode, a large-scale pattern of variability characterized by fluctuations in the strength of …

Efficient intracellular delivery of proteins is needed to fully realize the potential of protein
therapeutics. Current methods of protein delivery commonly suffer from low tolerance for serum, …