Background The sialic acid analogue zanamivir (GG167) is a selective inhibitor of influenza
A and B virus neuraminidases. These viral enzymes are essential for the release of virus …

Background Assessing the mortality impact of the 2009 influenza A H1N1 virus (H1N1pdm09)
is essential for optimizing public health responses to future pandemics. The World Health …

Background: Despite their potential for increased morbidity, 75% to 90% of asthmatic children
do not receive influenza vaccination. Live attenuated influenza vaccine (LAIV), a cold-…

Objectives To measure trends in antibiotic prescribing in UK primary care in relation to
nationally recommended best practice. Patients and methods A descriptive study linking …

… Douglas Fleming declares having received support for travel to international scientific …
Douglas Fleming also discloses the following conflicts of interest outside of submitted work: board …

A double-blind, randomized study of inhaled zanamivir for the prevention of influenza in
families was conducted. Once a person with a suspected case of influenza was identified (index …

… Douglas M Fleming, … Comparison of study methods: Thompson et al and Fleming et al … DM
Fleming has acted as an advisor and speaker on matters relating to influenza vaccination and …

OBJECTIVE. The goal was to evaluate the safety, tolerability, and efficacy of an
investigational, refrigerator-stable formulation of live attenuated influenza vaccine (cold-adapted …

Background Influenza is rarely confirmed with laboratory testing and accurate assessment
of the overall burden of influenza is difficult. We used statistical modelling methods to …

Objective The burden of respiratory syncytial virus (RSV) illness is not well characterised in
primary care. We estimated the burden of disease attributable to RSV in children in the UK …