Background Multimorbidity places a substantial burden on patients and the healthcare
system, but few contemporary epidemiological data are available. Aim To describe the …

The dielectric permittivity of a model fluid representing methyl cyanide has been studied
with a view to testing a recently developed theory of the frequency dependent dielectric …

Background The majority of people with dementia have other long-term diseases, the presence
of which may affect the progression and management of dementia. This study aimed to …

Developing a user-friendly platform that can handle a vast number of complex physiologically
based pharmacokinetic and pharmacodynamic (PBPK/PD) models both for conventional …

Objectives UK primary care databases (PCDs) are used by researchers worldwide to inform
clinical practice. These databases have been primarily tied to single clinical computer …

Atrial fibrillation (AF) is an arrhythmia of increasing prevalence associated with a reducible
risk of stroke. We conducted a systematic review to address five questions relating to how we …

BACKGROUND: Health services have failed to respond to the pressures of multimorbidity.
Improved measures of multimorbidity are needed for conducting research, planning services …

Background Multimorbidity is associated with mortality and service use, with specific types
of multimorbidity having differential effects. Additionally, multimorbidity is often negatively …

Background Trial and observational evidence is conflicting in terms of the association of
blood lipids, atherosclerosis and statin use with dementia and cognitive impairment in the …

PURPOSE Despite the compelling evidence supporting cardiovascular medications in the
secondary prevention of coronary artery disease, many patients discontinue treatment. In this …