User profiles for E Arnold
 | Eddy ArnoldBoard of Governors and Distinguished Professor of Chemistry and Chemical Biology … Verified email at cabm.rutgers.edu Cited by 33218 |
Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase: implications for mechanisms of …
…, R Pauwels, K Andries, PAJ Janssen, E Arnold - Journal of molecular …, 1994 - Elsevier
… We thank the other members of the Arnold and Hughes laboratories for their numerous
contributions … The work in Edward Arnold's laboratory has been supported by NlH grant Al 27690, …
contributions … The work in Edward Arnold's laboratory has been supported by NlH grant Al 27690, …
Structure of a human common cold virus and functional relationship to other picornaviruses
MG Rossmann, E Arnold, JW Erickson… - Nature, 1985 - nature.com
We report the first atomic resolution structure of an animal virus, human rhinovirus 14. It is
strikingly similar to known icosahedral plant RNA viruses. Four neutralizing immunogenic …
strikingly similar to known icosahedral plant RNA viruses. Four neutralizing immunogenic …
HIV reverse transcriptase structure-function relationships
A Jacobo-Molina, E Arnold - Biochemistry, 1991 - ACS Publications
Biochemical and mutagenesis studies performed on HIV-1 RT are reviewed in light of the
enzyme’s structure and functions. Features described include domain arrangement, …
enzyme’s structure and functions. Features described include domain arrangement, …
Epidemiology and natural history of urinary incontinence
S Hunskaar, EP Arnold, K Burgio, AC Diokno… - International …, 2000 - Springer
This paper examines or current state of knowledge of the epidemiology of urinary incontinence.
The population studied was community-dwelling non-institutionalized persons. The …
The population studied was community-dwelling non-institutionalized persons. The …
Isolation and structure of bryostatin 1
…, DL Doubek, DL Herald, E Arnold… - Journal of the …, 1982 - ACS Publications
Marine animals of the phylum Ectoprocta (usually termed Bryozoa or Polyzoa) are colonial
filter-feeders and each member (polypide) is enclosed in a separate unit (zooecium). …
filter-feeders and each member (polypide) is enclosed in a separate unit (zooecium). …
The site of attachment in human rhinovirus 14 for antiviral agents that inhibit uncoating
WIN 51711 and WIN 52084 are structurally related, antiviral compounds that inhibit the
replication of rhino (common cold) viruses and related picornaviruses. They prevent the pH-…
replication of rhino (common cold) viruses and related picornaviruses. They prevent the pH-…
[HTML][HTML] Crystal structure of HIV‐1 reverse transcriptase in complex with a polypurine tract RNA: DNA
…, JM Whitcomb, PL Boyer, SH Hughes, E Arnold - The EMBO …, 2001 - embopress.org
We have determined the 3.0 Å resolution structure of wild‐type HIV‐1 reverse transcriptase
in complex with an RNA: DNA oligonucleotide whose sequence includes a purine‐rich …
in complex with an RNA: DNA oligonucleotide whose sequence includes a purine‐rich …
Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab …
…, C Tantillo, SH Hughes, E Arnold - Journal of molecular …, 1998 - Elsevier
The structure of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT)
complexed with a 19-mer/18-mer double-stranded DNA template-primer (dsDNA) and the Fab …
complexed with a 19-mer/18-mer double-stranded DNA template-primer (dsDNA) and the Fab …
Structure of HIV-1 RT/TIBO R 86183 complex reveals similarity in the binding of diverse nonnucleoside inhibitors
…, K Andries, PAJ Janssen, SH Hughes, E Arnold - Nature structural …, 1995 - nature.com
We report the structure of HIV-1 reverse transcriptase (RT) complexed with the nonnucleoside
inhibitor TIBO R 86183 at 3.0 Å resolution. Comparing this structure with those of …
inhibitor TIBO R 86183 at 3.0 Å resolution. Comparing this structure with those of …
Emergence of human immunodeficiency virus type 1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosides.
…, S Chokekijchai, BM Roy, E Arnold… - Proceedings of the …, 1995 - National Acad Sciences
A set of mutations [Ala-62-->Val(A62V), V75I, F77L, F116Y, and Q151M] in the polymerase
domain of reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1) confers …
domain of reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1) confers …