Objective Early recognition and treatment of febrile children with serious infections (SI) improves
prognosis, however, early detection can be difficult. We aimed to validate the predictive …

Introduction and purpose of the study With this study we aimed to describe a “true world”
picture of severe paediatric ‘community-acquired’ septic shock and establish the feasibility of a …

Background Steam inhalation therapy is often recommended in the treatment of a common
cold. However, it has no proven benefit and may in fact have serious adverse side effects in …

Cow’s milk allergy (CMA) is the most common food allergy in early childhood. The golden
standard for the diagnosis of CMA is a food challenge after a period of elimination. Increased …

Objective To assess the feasibility and impact of a clinical decision model for febrile children
at risk for SBI attending the ED

A pharmacokinetic study was set up to investigate the pharmacokinetics of the anti-emetic
agents aprepitant and dexamethasone and the drug-drug interaction between these drugs in …

Background Childhood craniopharyngioma (cCP) has excellent survival, but quality of life
may be severely hampered by hypothalamic dysfunction. We aimed to evaluate treatment and …

We aimed to estimate clinicians’ based risk thresholds at which febrile children would be
managed as serious bacterial infections (SBI) to determine influencing characteristics and to …

Importance To improve diagnostics of cancer predisposition syndromes (CPSs) in children
with cancer, it is essential to evaluate the effect of CPS gene sequencing among all children …

Objectives To assess the impact of a clinical decision model for febrile children at risk for
serious bacterial infections (SBI) attending the emergency department (ED). Methods …