Historically, primary lymphoedema was classified into just three categories depending on
the age of onset of swelling; congenital, praecox and tarda. Developments in clinical …

Chronic plaques in central nervous system tissue fixed by in situe perfusion for electron
microscopy were examined for evidence of remyelination in 2 patients with multiple sclerosis (MS…

Objectives. Advances in medical technology and public health are changing the causes and
patterns of pediatric mortality. To better inform health care planning for dying children, we …

Fragile X syndrome [fra (X)] is currently accepted as the second most frequent chromosomal
disorder associated with developmental disability. Although next to Down syndrome in …

Milroy disease ( MD ) is an autosomal dominantly inherited primary lymphedema. In 1998,
the gene locus for MD was mapped to 5q35.3 and variants in the VEGFR3 (FLT4) gene, …

Context. The benefits of continuity of pediatric care remain controversial. Objective. To
determine whether there is an association between having a continuous relationship with a …

Background Adverse-event reports from North America have raised concern that the use of
drugs for attention deficit–hyperactivity disorder (ADHD) increases the risk of serious …

We report an allelic series of eight mutations in GATA2 underlying Emberger syndrome, an
autosomal dominant primary lymphedema associated with a predisposition to acute myeloid …

Microcephaly with or without chorioretinopathy, lymphoedema, or mental retardation (MCLMR)(MIM
No. 152950) is a rare autosomal dominant condition for which a causative gene has …

Background Prior studies have had conflicting results regarding the relationship between
adolescent depression and adult obesity. Objective To test the hypothesis that depression in …