Histological grade heterogeneity in multifocal prostate cancer. Biological and clinical implications

…, JA SCHALKEN, FM DEBRUYNE… - The Journal of …, 1996 - Wiley Online Library
In order to understand the clinical and biological implications of prostate cancer multifocality
and heterogeneity, we investigated their occurrence in relation to variables such as tumour …

Controlled trial of pelvic floor exercises in the treatment of urinary stress incontinence in general practice.

TL Lagro-Janssen, FM Debruyne, AJ Smits… - British Journal of …, 1991 - bjgp.org
The aim of this study was to assess the usefulness of pelvic floor exercises in the treatment
of urinary incontinence in women and to analyse the factors which determine a successful …

fur gene expression as a discriminating marker for small cell and nonsmall cell lung carcinomas.

…, SS Wagenaar, FM Debruyne… - The Journal of …, 1987 - Am Soc Clin Investig
The recently discovered fur gene encodes a membrane-associated protein with a recognition
function. To further characterize the gene, we studied its expression by Northern blot …

The role of nocturia in the quality of life of men with lower urinary tract symptoms

MM Van Dijk, H Wijkstra, FM Debruyne… - BJU …, 2010 - Wiley Online Library
Study Type – Symptom prevalence (retrospective cohort) Level of Evidence 2b OBJECTIVES
To determine the role of treatment‐associated improvement in nocturia in health‐related …

Role of testosterone in managing advanced prostate cancer

KO Rove, FM Debruyne, B Djavan, LG Gomella… - Urology, 2012 - Elsevier
Androgen deprivation therapy is frequently used to treat patients with advanced prostate
cancer. New therapies for metastatic castration-resistant prostate cancer have drawn increased …

Should random urothelial biopsies be taken from patients with primary superficial bladder cancer? A decision analysis. Members of the Dutch South-East Co …

…, NP Koper, AL Verbeek, FM Debruyne - British journal of …, 1994 - europepmc.org
Objective To evaluate whether it is worthwhile to implement routine random biopsies from
the normal-looking urothelium in the management of patients with primary superficial …

Correlation of transrectal ultrasound, computer analysis of transrectal ultrasound and histopathology of radical prostatectomy specimen

…, H Wijkstra, CA van de Kaa, FM Debruyne… - Prostate cancer and …, 2001 - nature.com
A system for computerised analysis of ultrasonographic prostate images (AUDEX= Automated
Urologic Diagnostic EXpert system) for the detection of prostate carcinoma was developed…

Rapid microwave‐stimulated fixation of entire prostatectomy specimens

…, JA Schalken, FM Debruyne… - The Journal of …, 1997 - Wiley Online Library
Conventional fixation of large solid surgical specimens is a slow process. Consequently,
autolytic damage to tissues may occur if the fixative does not reach the central part of the …

A retrospective study of high mobility group protein I (Y) as progression marker for prostate cancer determined by in situ hybridization

…, HG van der Poel, HFM Karthaus, FM Debruyne… - British journal of …, 1996 - nature.com
In a previous study using RNA in situ hybridisation (RISH), we found a significant correlation
between high mobility group protein I/Y,[HMG-I (Y)] mRNA expression and tumour stage …

Expression of cadherin-6 as a novel diagnostic tool to predict prognosis of patients with E-cadherin-absent renal cell carcinoma.

…, JO Wakka, A van Bokhoven, FM Debruyne… - Clinical cancer research …, 1998 - AACR
In many carcinomas, E-cadherin is considered to be a prognostic marker for patient survivals,
and its decreased expression is associated with metastatic disease. Among renal cell …