AMPK: a nutrient and energy sensor that maintains energy homeostasis
DG Hardie, FA Ross, SA Hawley - Nature reviews Molecular cell biology, 2012 - nature.com
AMP-activated protein kinase (AMPK) is a crucial cellular energy sensor. Once activated by
falling energy status, it promotes ATP production by increasing the activity or expression of …
falling energy status, it promotes ATP production by increasing the activity or expression of …
Genetic regulation of osteoclast development and function
SL Teitelbaum, FP Ross - Nature Reviews Genetics, 2003 - nature.com
Osteoclasts are the principal, if not exclusive, bone-resorbing cells, and their activity has a
profound impact on skeletal health. So, disorders of skeletal insufficiency, such as …
profound impact on skeletal health. So, disorders of skeletal insufficiency, such as …
Electron microscopy of specimens in liquid
N De Jonge, FM Ross - Nature nanotechnology, 2011 - nature.com
… f, Combination of SEM and light microscopy of a liquid sample above an electron … & Ross,
FM Dynamic microscopy of nanoscale cluster growth at the solid–liquid interface. Nature Mater…
FM Dynamic microscopy of nanoscale cluster growth at the solid–liquid interface. Nature Mater…
[HTML][HTML] TNF-α induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand
…, JE Barker, O Kanagawa, FP Ross… - The Journal of …, 2000 - Am Soc Clin Investig
While TNF-α is pivotal to the pathogenesis of inflammatory osteolysis, the means by which it
recruits osteoclasts and promotes bone destruction are unknown. We find that a pure …
recruits osteoclasts and promotes bone destruction are unknown. We find that a pure …
Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders
…, C Bryant, AV Jones, K Waghorn, K Zoi, FM Ross… - Nature …, 2010 - nature.com
Abnormalities of chromosome 7q are common in myeloid malignancies, but no specific
target genes have yet been identified. Here, we describe the finding of homozygous EZH2 …
target genes have yet been identified. Here, we describe the finding of homozygous EZH2 …
The influence of the surface migration of gold on the growth of silicon nanowires
Interest in nanowires continues to grow, fuelled in part by applications in nanotechnology 1 ,
2 , 3 , 4 , 5 . The ability to engineer nanowire properties makes them especially promising in …
2 , 3 , 4 , 5 . The ability to engineer nanowire properties makes them especially promising in …
[HTML][HTML] IL-1 mediates TNF-induced osteoclastogenesis
S Wei, H Kitaura, P Zhou, FP Ross… - The Journal of …, 2005 - Am Soc Clin Investig
TNF-induced receptor activator NF-κB ligand (RANKL) synthesis by bone marrow stromal
cells is a fundamental component of inflammatory osteolysis. We found that this process was …
cells is a fundamental component of inflammatory osteolysis. We found that this process was …
[HTML][HTML] A randomized trial of convalescent plasma in Covid-19 severe pneumonia
…, W Cornistein, OA Trabadelo, FM Ross… - … England Journal of …, 2021 - Mass Medical Soc
Background Convalescent plasma is frequently administered to patients with Covid-19 and
has been reported, largely on the basis of observational data, to improve clinical outcomes. …
has been reported, largely on the basis of observational data, to improve clinical outcomes. …
[HTML][HTML] β3-integrin–deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival
…, D Crowley, M Ullman-Culleré, FP Ross… - The Journal of …, 1999 - Am Soc Clin Investig
β3 integrins have been implicated in a wide variety of functions, including platelet aggregation
and thrombosis (αIIbβ3) and implantation, placentation, angiogenesis, bone remodeling, …
and thrombosis (αIIbβ3) and implantation, placentation, angiogenesis, bone remodeling, …
[HTML][HTML] Mice lacking β3 integrins are osteosclerotic because of dysfunctional osteoclasts
…, J Lam, D Novack, X Feng, FP Ross… - The Journal of …, 2000 - Am Soc Clin Investig
Osteoclasts express the αvβ3 integrin, an adhesion receptor that has been implicated in
bone resorption and that is therefore a potential therapeutic target. To assess the role of this …
bone resorption and that is therefore a potential therapeutic target. To assess the role of this …