Social and economic effects of mood disorders include functional impairment, disability or
lost work productivity, and increased use of health services. Evidence for these impacts …

Depression is second only to hypertension as the most common chronic condition encountered
in general medical practice. At least 1 in 10 outpatients has major depression, but most …

… The randomized trial by Simon et al 28 similarly found patients more likely to discontinue …
In a prospective randomized trial, Simon et al 19 compared clinical outcomes and treatment …

Context.—There is little information on the extent of persistent pain across cultures. Even
though pain is a common reason for seeking health care, information on the frequency and …

… Simon GE. Psychiatric disorder and functional symptoms as predictors of health care use. …
Simon GE, Von Korff M. Somatization and psychiatric disorder in the NIMH Epidemiologic …

Background Patients with depression, particularly those seen by primary care physicians, may
report somatic symptoms, such as headache, constipation, weakness, or back pain. Some …

Background Epidemiologic data suggest an association between obesity and depression,
but findings vary across studies and suggest a stronger relationship in women than men. …

OBJECTIVE—We assessed whether diabetes self-care, medication adherence, and use of
preventive services were associated with depressive illness. RESEARCH DESIGN AND …

… Wang PS, Simon GE, Kessler RC: The economic burden of depression and the cost-effectiveness
of treatment. Int J Methods Psychiatr Res 2003; 12:22–33Google Scholar …

Objective: The prevalence, burden, and management of insomnia among primary care
patients were evaluated. Method: Consecutive patients aged 18 to 65 years in primary care …