Cells have distinct mechanisms to maintain protection against different reactive oxygen species: oxidative-stress-response genes

GW Thorpe, CS Fong, N Alic… - Proceedings of the …, 2004 - National Acad Sciences
The complete set of viable deletion strains in Saccharomyces cerevisiae was screened for
sensitivity of mutants to five oxidants to identify cell functions involved in resistance to …

Superoxide radicals have a protective role during H2O2 stress

GW Thorpe, M Reodica, MJ Davies… - Molecular biology of …, 2013 - Am Soc Cell Biol
Reactive oxygen species (ROS) consist of potentially toxic, partly reduced oxygen species
and free radicals. After H 2 O 2 treatment, yeast cells significantly increase superoxide radical …

Phenotypic analysis of gene deletant strains for sensitivity to oxidative stress

VJ Higgins, N Alic, GW Thorpe, M Breitenbach… - Yeast, 2002 - Wiley Online Library
Ascertaining the impact of inhibitors on the growth phenotype of yeast mutants can beuseful
in elucidating the function of genes within the cell. Microtitre plates and robotics have been …

Adaptation to hydrogen peroxide in Saccharomyces cerevisiae: the role of NADPH-generating systems and the SKN7 transcription factor

CH Ng, SX Tan, GG Perrone, GW Thorpe… - Free Radical Biology …, 2008 - Elsevier
A total of 286 H 2 O 2 -sensitive Saccharomyces cerevisiae deletion mutants were screened
to identify genes involved in cellular adaptation to H 2 O 2 stress. YAP1, SKN7, GAL11, …

[HTML][HTML] Effects on quality of life, anti-cancer responses, breast conserving surgery and survival with neoadjuvant docetaxel: a randomised study of sequential weekly …

…, JA Jibril, D Valerio, DJ Clarke, M Kamal, GW Thorpe… - BMC cancer, 2011 - Springer
Background Weekly docetaxel has occasionally been used in the neoadjuvant to downstage
breast cancer to reduce toxicity and possibly enhance quality of life. However, no studies …

Oxidant-induced cell-cycle delay in Saccharomyces cerevisiae: the involvement of the SWI6 transcription factor

…, N Alic, J Chiu, M Durchdewald, GW Thorpe… - FEMS yeast …, 2008 - academic.oup.com
Cells treated with low doses of linoleic acid hydroperoxide (LoaOOH) exhibit a cell-cycle delay
that may provide a mechanism to overcome oxidative stress. Strains sensitive to LoaOOH …

3 cases of longitudinal stress fracture of the tibia

JF Keating, I Beggs, GW Thorpe - Acta Orthopaedica Scandinavica, 1995 - Taylor & Francis
A 62-year-old man rose from a crouched position with a twisting motion and developed pain
in the lower third of his left tibia. 2 weeks later, radiographs were normal. Pain persisted and …

New results in the theory of elasticity for two-dimensional composites

MF Thorpe, I JaSIUK - … of the Royal Society of London …, 1992 - royalsocietypublishing.org
… We have had extensive correspondence with GW Milton, who has supplied us with an
unpublished proof of this theorem. This proof is now available in the paper by Cherkaev et al. (…

[BOOK][B] The turbulent ocean

SA Thorpe - 2005 - books.google.com
The subject of ocean turbulence is in a state of discovery and development with many
intellectual challenges. This book describes the principal dynamic processes that control the …

Dissipation in hydraulic transitions in flows through abyssal channels

SA Thorpe - Journal of Marine Research, 2007 - ingentaconnect.com
There is growing evidence from observations that mixing occurs in hydraulic jumps, or flow
transitions, downstream of sills within channels connecting deep ocean basins or within …