Background—Associations have been shown between irritable bowel syndrome (IBS) and
gastro-oesophageal reflux, between gastro-oesophageal reflux and asthma, and more …

Long-term proton pump inhibitor (PPI) prescribing in general practice is common, but only a
minority of patients request their prescriptions regularly. This study determined factors linked …

… H O’Flanagan, DCRT, NoReN research coordinator, The Health Centre, Eaglescliffe, …
A Pali S Hungin, GP Rubin and H O’Flanagan … A Pali S Hungin, GP Rubin and H O’Flanagan …

Background Outbreaks of sexually transmitted Shigella flexneri and Shigella sonnei in men
who have sex with men (MSM) are a major public health issue. While most cases can be …

Background Outbreaks of sexually transmitted shigella have been reported in men who
have sex with men (MSM) since the 1970s and present a major public health issue. …

Calorie restriction (CR) extends lifespan and has been shown to reduce age-related
diseases including cancer, diabetes, and cardiovascular and neurodegenerative diseases in …

Background Single-cell RNA sequencing (scRNA-seq) is a powerful tool for studying complex
biological systems, such as tumor heterogeneity and tissue microenvironments. However, …

How cell-to-cell copy number alterations that underpin genomic instability 1 in human
cancers drive genomic and phenotypic variation, and consequently the evolution of cancer 2 , …

Numerous epidemiological and pre-clinical studies have demonstrated that the insulin/insulin-like
growth factor (IGF) system plays a key role in the development and progression of …

Objective Self-monitoring asthma control is a key component of asthma management. Few
studies have reported usability and acceptability of portable spirometry among young adults …