Background Interventions to prevent influenza-related complications are recommended for
individuals at the greatest risk of serious clinical deterioration. However, guidelines are …

Background GPs report the lowest levels of morale among doctors, job satisfaction is low,
and the GP workforce is diminishing. Workload is frequently cited as negatively impacting on …

Background The existence of a crisis in primary care in the UK is in little doubt. GP morale
and job satisfaction are low, and workload is increasing. In this challenging context, finding …

Background Pertussis (whooping cough) is a highly infective cause of cough that causes
significant morbidity and mortality. Existing case definitions include paroxysmal cough, …

Objective To assess the diagnostic accuracy of pain on travelling over speed bumps for the
diagnosis of acute appendicitis. Design Prospective questionnaire based diagnostic …

Objectives National Institute for Health and Care Excellence guidelines recommend immediate
antibiotic treatment of respiratory tract infections in ‘at-risk’ individuals with comorbidities. …

… HF Ashdown drafted the manuscript for submission and received critical input from all authors.
HF Ashdown … Conflict of interest: HF Ashdown reports support for the present manuscript …

… would like to thank the study participants, and those colleges of the University of Oxford and
public houses in Oxford which permitted them to recruit on their premises; Michael Ashdown …

… Helen Ashdown’s academic department receives money for her role in a collaborative
project with Boehringer Ingelheim Ltd. We declare that none of the authors has competing …

Objective Observational studies have suggested a beneficial effect of taking statins on
frequency of chronic obstructive pulmonary disease (COPD) exacerbations. However, clinical …