High-intensity interval training in patients with lifestyle-induced cardiometabolic disease: a systematic review and meta-analysis

KS Weston, U Wisløff, JS Coombes - British journal of sports medicine, 2014 - bjsm.bmj.com
Background/Aim Cardiorespiratory fitness (CRF) is a strong determinant of morbidity and
mortality. In athletes and the general population, it is established that high-intensity interval …

Triple-negative breast cancer: therapeutic options

S Cleator, W Heller, RC Coombes - The lancet oncology, 2007 - thelancet.com
Triple-negative breast cancers are defined by a lack of expression of oestrogen, progesterone,
and ERBB2 receptors. This subgroup accounts for 15% of all types of breast cancer and …

Endocrine-responsive breast cancer and strategies for combating resistance

S Ali, RC Coombes - Nature Reviews Cancer, 2002 - nature.com
Deaths from breast cancer have fallen markedly over the past decade due, in part, to the
use of endocrine agents that reduce the levels of circulating oestrogens or compete with …

Folate and ageing

RC Coombes, LS Kilburn, CF Snowdon - cancer, 2004 - thelancet.com
The FACIT trial of folic acid supple mentation in older adults by Jane Durga and colleagues (Jan
20, p 208) 1 adds to the growing evidence of the importance of folate to the nervous …

Laion-5b: An open large-scale dataset for training next generation image-text models

…, R Wightman, M Cherti, T Coombes… - Advances in …, 2022 - proceedings.neurips.cc
Groundbreaking language-vision architectures like CLIP and DALL-E proved the utility of
training on large amounts of noisy image-text data, without relying on expensive accurate …

[BOOK][B] Reinventing Africa: museums, material culture, and popular imagination in late Victorian and Edwardian England

AE Coombes - 1994 - books.google.com
Between 1890 and 1918, British colonial expansion in Africa led to the removal of many
African artifacts that were subsequently brought to Britain and displayed. Annie Coombes

[HTML][HTML] Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled …

…, R Colin-Jones, CP Conlon, A Cook, NS Coombes… - The Lancet, 2020 - thelancet.com
Background The pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
might be curtailed by vaccination. We assessed the safety, reactogenicity, and …

A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β– and retinoic acid–dependent mechanism

JL Coombes, KRR Siddiqui… - The Journal of …, 2007 - rupress.org
Foxp3 + regulatory T (T reg) cells play a key role in controlling immune pathological re
actions. Many develop their regulatory activity in the thymus, but there is also evidence for …

[HTML][HTML] Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind …

…, E Clark, S Collins, CP Conlon, NS Coombes… - The Lancet, 2020 - thelancet.com
Background Older adults (aged ≥70 years) are at increased risk of severe disease and
death if they develop COVID-19 and are therefore a priority for immunisation should an …

[HTML][HTML] Evidence of escape of SARS-CoV-2 variant B. 1.351 from natural and vaccine-induced sera

…, J Slon-Campos, B Hallis, N Coombes… - Cell, 2021 - cell.com
The race to produce vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
began when the first sequence was published, and this forms the basis for …