Background Immune checkpoint inhibitors are a new standard of care for patients with
advanced non-small-cell lung cancer (NSCLC) without EGFR tyrosine kinase or anaplastic …

Adult marrow‐derived Mesenchymal Stem Cells (MSCs) are capable of dividing and their
progeny are further capable of differentiating into one of several mesenchymal phenotypes …

Cell-surface receptors frequently use scaffold proteins to recruit cytoplasmic targets, but the
rationale for this is uncertain. Activated receptor tyrosine kinases, for example, engage …

Background: Despite the well‐documented risk factors and health consequences of postpartum
depression, it often remains undetected and untreated. No study has comprehensively …

We are delighted that SIAM is republishing our original 1983 book after what many in the
optimization field have regarded as “premature termination” by the previous publisher. At 12 …

The distributed nature of biological knowledge poses a major challenge to the interpretation
of genome-scale datasets, including those derived from microarray and proteomic studies. …

Cerebral deposition of amyloid β peptide (Aβ) is an early and critical feature of Alzheimer's
disease. Aβ generation depends on proteolytic cleavage of the amyloid precursor protein (…

We describe the incidence and natural history of four clinically identifiable subgroups of
cerebral infarction in a community-based study of 675 patients with first-ever stroke. Of 543 …

… This book has a running online case study (accessible from www.wiley.com/go/dennis/ …
at www.wiley.com/college/dennis. These boxes describe how real companies succeeded—and …

PHAge Search Tool (PHAST) is a web server designed to rapidly and accurately identify,
annotate and graphically display prophage sequences within bacterial genomes or plasmids. It …