The transplantation of pig organs to humans (xenotransplantation) is now receiving serious
consideration because of the shortage of human donors for organ transplants of kidney, liver …

A major problem with pig-to-human-tissue xenograft studies is that humans have natural
antibodies to pig cells; these antibodies would cause hyperacute rejection if pig tissues were …

Mucin 1 (MUC1) is a large complex glycoprotein that is highly expressed in breast cancer,
and as such could be a target for immunotherapy. In mice, human MUC1 is highly …

… The unusual finding is that if the conjugation is done under oxidizing conditions, then cell-mediated
immunity is selectively stimulated, compared with using reducing conditions for …

… all patients should exhibit an immune response if the therapy is working, and a … We consider
these characteristics to be crucial if … of patients) if meaningful results are to be to obtained. …

The proto-oncogene pim-1 is a serine/threonine kinase the over-expression of which
promotes lymphoma formation. Neither the normal function of Pim-1 nor the biochemical …

Human IgG Fc receptor (Fc gamma R) cDNA clones were isolated by cross-species hybridization
by probing cDNA libraries with the low-affinity Fc gamma R beta 1 cDNA clone from …

The development of an effective immunotherapeutic approach to cancer is now a major
focus of research, and despite impressive progress over the last 10 years there are still many …

… Attempts are also under way to produce a strain of resistant mice congenic with BALB/c,
which, if successful, will provide stronger evidence of a single gene. It was important to …

The B6.CH-2bm12 mutant is described and evidence is presented for the mutational site
occurring in the IA subregion. The mutant is of the gain and loss type as bm12 in equilibrium or …