[HTML][HTML] The methyl donor S-adenosylmethionine inhibits active demethylation of DNA: a candidate novel mechanism for the pharmacological effects of S …

N Detich, S Hamm, G Just, JD Knox, M Szyf - Journal of Biological …, 2003 - ASBMB
S-Adenosylmethionine (AdoMet) is the methyl donor of numerous methylation reactions.
The current model is that an increased concentration of AdoMet stimulates DNA …

Differential expression of extracellular matrix molecules and the alpha 6-integrins in the normal and neoplastic prostate.

JD Knox, AE Cress, V Clark, L Manriquez… - The American journal …, 1994 - ncbi.nlm.nih.gov
The epithelial basal lamina composition and integrin expression profile of normal and
neoplastic human prostate was characterized using immunohistochemical analysis of frozen …

Expression of hemidesmosomal and extracellular matrix proteins by normal and malignant human prostate tissue.

RB Nagle, J Hao, JD Knox, BL Dalkin… - The American journal …, 1995 - ncbi.nlm.nih.gov
The progression of prostate carcinoma may be influenced by the biochemical nature of the
basal lamina surrounding the primary carcinoma cells. As a first step toward understanding …

Biological variability of 26 clinical chemistry analytes in elderly people.

…, SP Wilkinson, RG Neville, JD Knox… - Clinical …, 1989 - academic.oup.com
Analytical, within-subject, and between-subject components of variation were estimated for
26 clinical chemistry analytes from duplicate analyses of 10 specimens collected from 27 …

Expression of the metalloproteinase matrilysin in DU-145 cells increases their invasive potential in severe combined immunodeficient mice

WC Powell, JD Knox, M Navre, TM Grogan, J Kittelson… - Cancer research, 1993 - AACR
Human prostate cancer displays a high degree of variability in its rate of spread, which could
be due largely to differences in the invasive potential of the tumor cells. The degradation of …

Coactivation of NMDA Receptors by Glutamate and d-Serine Induces Dilation of Isolated Middle Cerebral Arteries

…, MJ Stobart, L Lu, JD Knox… - Journal of Cerebral …, 2012 - journals.sagepub.com
N-methyl-d-aspartate (NMDA) receptors are glutamate-gated cation channels that mediate
excitatory neurotransmission in the central nervous system. In addition to glutamate, NMDA …

[HTML][HTML] DNA methyltransferase inhibition induces the transcription of the tumor suppressor p21 WAF1/CIP1/sdi1

S Milutinovic, JD Knox, M Szyf - Journal of Biological Chemistry, 2000 - ASBMB
Previous lines of evidence have shown that inhibition of DNA methyltransferase (MeTase)
can arrest tumor cell growth; however, the mechanisms involved were not clear. In this …

Matrilysin expression in human prostate carcinoma

JD Knox, C Wolf, K McDaniel, V Clark… - … in cooperation with …, 1996 - Wiley Online Library
The metalloproteinases, a multigene family of metal‐requiring enzymes, have been suggested
to play a role in tumor invasion and metastasis. Previously, we demonstrated that human …

Adhesion molecules, extracellular matrix, and proteases in prostate carcinoma.

RB Nagle, JD Knox, C Wolf, GT Bowden… - Journal of Cellular …, 1994 - europepmc.org
Immunohistochemical studies of prostate carcinoma reveal that most primary carcinomas,
including high-grade tumors, are surrounded by a basal lamina composed of laminin, type IV …

Rapid, sensitive, and specific Escherichia coli H antigen typing by matrix-assisted laser desorption ionization–time of flight-based peptide mass fingerprinting

…, B Xu, M Drebot, C Nadon, JD Knox… - Journal of clinical …, 2015 - Am Soc Microbiol
… Nadon, and JD Knox contributed project ideas and critical writing; G. Westmacott … A,
Westmacott G, Drebot M, Nadon C, Knox JD, Wang G. 2014. Comparative study of … David Knox