Background Postal self-completion questionnaires offer one of the least expensive modes of
collecting patient based outcomes in health care research. The purpose of this review is to …

: Purpose: Gabapentin (GBP), lamotrigine (LTG), tiagabine (TGB), topiramate (TPM),
vigabatrin (VGB), and zonisamide (ZNS) are all in use as “add‐on” treatment for patients with …

The inverse of the difference between rates, called the ‘number needed to treat’ (NNT), was
suggested 20 years ago as a good way to present the results of comparisons of success or …

In a meta‐analysis of randomized controlled trials with time‐to‐event outcomes, an aggregate
data approach may be required for some or all included studies. Variation in the reporting …

Background Severe ankle sprains are a common presentation in emergency departments in
the UK. We aimed to assess the effectiveness of three different mechanical supports (Aircast …

GRACILE (growth retardation, aminoaciduria, cholestasis, iron overload, lactacidosis, and
early death) syndrome is a recessively inherited lethal disease characterized by fetal growth …

Alterations in taste and smell functions have been reported in cancer patients. Although
these senses are known to be particularly affected by chemotherapy, many features of …

Although bias in meta-analysis arising from selective publication has been studied, within-study
selection has received little attention. Chronic diseases often have several possible …

Recent research has shown that reading disabled children find it unusually difficult to detect
flickering or moving visual stimuli, consistent with impaired processing in the magnocellular …

Publication bias has been previously identified as a threat to the validity of a meta-analysis.
Recently, new evidence has documented an additional threat to validity, the selective …