Molecular engineering of guanine-rich sequences: Z-DNA, DNA triplexes, and G-quadruplexes

O Doluca, JM Withers, VV Filichev - Chemical reviews, 2013 - ACS Publications
Guanine’s array of hydrogen bond donors and acceptors lead it to take part in structures as
diverse as B-DNA, Z-DNA, hairpins, cruciforms, triplexes, and G-quadruplexes; these …

Granulosa cell tumours in the mare: A review of 52 cases

…, K Lott‐Ellis, A Bergren, JM Withers… - Equine Veterinary …, 2016 - Wiley Online Library
Granulosa cell tumour ( GCT ) is reported to be the most common ovarian neoplasm in the
mare. A multicentre retrospective study evaluating the medical records of horses undergoing …

Radiographic anatomy of the articular process joints of the caudal cervical vertebrae in the horse on lateral and oblique projections

JM Withers, LC Voute, G Hammond… - Equine veterinary …, 2009 - Wiley Online Library
Reasons for performing study: Plain radiography is the standard imaging technique for
investigation of diseases associated with the articular process joints (APJ) of the caudal neck; …

Optimization and stability of glucoamylase production by recombinant strains of Aspergillus niger in chemostat culture

JM Withers, RJ Swift, MG Wiebe… - Biotechnology and …, 1998 - Wiley Online Library
When grown on a medium containing 5 g maltodextrin L −1 , Aspergillus niger transformant
N402[pAB6‐10]B1, which has an additional 20 copies of the glucoamylase (glaA) gene, …

Fluorous-directed assembly of DNA origami nanostructures

J Zou, AC Stammers, A Taladriz-Sender, JM Withers… - ACS …, 2022 - ACS Publications
An orthogonal, noncovalent approach to direct the assembly of higher-order DNA origami
nanostructures is described. By incorporating perfluorinated tags into the edges of DNA …

Synthetic biological approaches for RNA labelling and imaging: design principles and future opportunities

S Pauff, JM Withers, IJW McKean, SP Mackay… - Current opinion in …, 2017 - Elsevier
Highlights • Contemporary strategies for site-specific labelling of RNA are described. • Non-natural
nucleotides offer opportunities to install functional groups at defined sites within RNA …

Sequence-selective minor groove recognition of a DNA duplex containing synthetic genetic components

G Padroni, JM Withers, A Taladriz-Sender… - Journal of the …, 2019 - ACS Publications
The structural basis of minor groove recognition of a DNA duplex containing synthetic genetic
information by hairpin pyrrole-imidazole polyamides is described. Hairpin polyamides …

[HTML][HTML] Reversible DNA micro-patterning using the fluorous effect

GE Flynn, JM Withers, G Macias, JR Sperling… - Chemical …, 2017 - pubs.rsc.org
We describe a new method for the immobilisation of DNA into defined patterns with sub-micron
resolution, using the fluorous effect. The method is fully reversible via a simple solvent …

Increased plasma fructosamine concentrations in laminitic horses

EJ Knowles, JM Withers, TS Mair - Equine veterinary journal, 2012 - Wiley Online Library
Reasons for performing study: The use of plasma fructosamine concentration ([fructosamine])
as a marker of abnormal glucose homeostasis in laminitic horses has not been investigated…

Ultrasonography can be used to predict the location of manica flexoria tears in horses

…, F Cavallier, F Cantatore, JM Withers… - Equine Veterinary …, 2023 - Wiley Online Library
Background Manica flexoria (MF) tears are a well‐recognised cause of lameness in horses
presenting with effusion of the digital flexor tendon sheath (DFTS). Ultrasonography (US) is a …