OBJECTIVES. To review the available evidence on the value of routine preoperative testing
in healthy or asymptomatic adults. To assess the completeness of existing reviews of …

OBJECTIVES. To systematically review the literature on inborn errors of metabolism,
neonatal screening technology and screening programmes in order to analyse the costs and …

Background Randomised controlled trials (RCTs) are the gold standard assessment for
health technologies. A key aspect of the design of any clinical trial is the target sample size. …

A novel tumor necrosis factor (TNF) family member has been cloned and characterized. This
protein, designated TNF-related apoptosis-Inducing ligand (TRAIL), consists of 291 and …

Surgery and other invasive therapies are complex interventions, the assessment of which is
challenged by factors that depend on operator, team, and setting, such as learning curves, …

… Jon Nicholl, professor1 … O’Cathain A, Nicholl J, Murphy E. Structural issues affecting
mixed methods studies in health research: a qualitative study. BMC Med Res Methodol 2009;9:82 …

Objectives: Many claims are made that complementary medicine use is a substantial and
growing part of health-care behaviour. Estimates of practitioner visits in the USA and Australia …

Objectives To assess the quality of mixed methods studies in health services research (HSR).
Methods We identified 118 mixed methods studies funded by the Department of Health in …

Intercellular adhesion molecules play an important role in the generation of T lymphocyte–mediated
immune responses. Here, we describe a novel accessory molecule, DNAX …

XLFRAC is a simple program which solves linear least-squares mass-balance equations,
makes “subtraction diagram” calculations and can trace the composition of derivative magmas …