Risk for myopathy with statin therapy in high-risk patients
…, E Leitersdorf, W März, JPD Reckless… - Archives of internal …, 2003 - jamanetwork.com
Emerging data suggest that the 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase
inhibitors (statins) offer important benefits for the large population of individuals at high …
inhibitors (statins) offer important benefits for the large population of individuals at high …
Pitavastatin
…, J Reid, JPD Reckless - International journal of …, 2005 - Wiley Online Library
The growing number of trials that have highlighted the benefit of intensive lowering of total‐
and low density lipoprotein (LDL)‐cholesterol levels especially with statins has created a …
and low density lipoprotein (LDL)‐cholesterol levels especially with statins has created a …
Apolipoprotein E modulates clearance of apoptotic bodies in vitro and in vivo, resulting in a systemic proinflammatory state in apolipoprotein E-deficient mice
DJ Grainger, J Reckless, E McKilligin - The Journal of Immunology, 2004 - journals.aai.org
Apolipoprotein E (apoE) is a 34-kDa glycoprotein involved in lipoprotein transport through
interaction with the low-density lipoprotein receptor and related receptors. Recently, it has …
interaction with the low-density lipoprotein receptor and related receptors. Recently, it has …
Statin-induced myositis: a commonly encountered or rare side effect?
RYA Mukhtar, JPD Reckless - Current opinion in lipidology, 2005 - journals.lww.com
Conclusion As most individuals on statins are ‘high-risk’patients, they tend to be on multiple
agents for cardiovascular disease which may interact with their statin. Progression of …
agents for cardiovascular disease which may interact with their statin. Progression of …
Lipoproteins and their subfractions in psoriatic arthritis: identification of an atherogenic profile with active joint disease
…, J Lloyd, CA Stirling, JPD Reckless… - Annals of the …, 2000 - ard.bmj.com
OBJECTIVES (a) To characterise the lipid profile in psoriatic arthritis and investigate whether
there are similarities to the dyslipoproteinaemia reported in rheumatoid arthritis and other …
there are similarities to the dyslipoproteinaemia reported in rheumatoid arthritis and other …
MRC BHF Heart Protection Study of cholesterol-lowering therapy and of antioxidant vitamin supplementation in a wide range of patients at increased risk of coronary …
…, H McMahon, D Cheetham, J Reckless… - European Heart …, 1999 - eprints.ncl.ac.uk
… , Labib M, Pearson R, Sidaway J, Davies P, Hodgkiss M, MacLeod D, Stuart R, Albrock J,
Fisher J, Stuart F, Swainson C, Johnston J, Sadler S, Curren M, Feirnie S, Stenhouse L, Lindley …
Fisher J, Stuart F, Swainson C, Johnston J, Sadler S, Curren M, Feirnie S, Stenhouse L, Lindley …
Feasibility and indicative results from a 12-month low-energy liquid diet treatment and maintenance programme for severe obesity
… John Reckless is a non-executive director of Counterweight Ltd and holds shares in the
company. Nick Finer holds shares in Counterweight Ltd. Hazel Ross and Louise McCombie are …
company. Nick Finer holds shares in Counterweight Ltd. Hazel Ross and Louise McCombie are …
[HTML][HTML] Intensive versus guideline blood pressure and lipid lowering in patients with previous stroke: main results from the pilot 'Prevention of Decline in Cognition …
…, A Burns, J Mant, P Passmore, S Pocock, J Reckless… - PloS one, 2017 - journals.plos.org
Background Stroke is associated with the development of cognitive impairment and dementia.
We assessed the effect of intensive blood pressure (BP) and/or lipid lowering on cognitive …
We assessed the effect of intensive blood pressure (BP) and/or lipid lowering on cognitive …
[HTML][HTML] Anaesthetic Impairment of Immune Function Is Mediated via GABAA Receptors
DW Wheeler, AJ Thompson, F Corletto, J Reckless… - PloS one, 2011 - journals.plos.org
Background GABA A receptors are members of the Cys-loop family of neurotransmitter
receptors, proteins which are responsible for fast synaptic transmission, and are the site of action …
receptors, proteins which are responsible for fast synaptic transmission, and are the site of action …
Efficacy and safety of rosuvastatin 40 mg versus atorvastatin 80 mg in high-risk patients with hypercholesterolemia: results of the POLARIS study
LA Leiter, RS Rosenson, E Stein, JPD Reckless… - Atherosclerosis, 2007 - Elsevier
POLARIS investigated the efficacy and safety of rosuvastatin 40mg and atorvastatin 80mg in
high-risk patients with hypercholesterolemia. Patients (n=871) were randomized to …
high-risk patients with hypercholesterolemia. Patients (n=871) were randomized to …