User profiles for J Setters

Jane Setter

- Verified email at reading.ac.uk - Cited by 1695

Jeff Setter

- Verified email at stanford.edu - Cited by 600

Reducing hydrophobicity of homogeneous antibody-drug conjugates improves pharmacokinetics and therapeutic index

…, M Jonas, ME Anderson, JR Setter… - Nature …, 2015 - nature.com
The in vitro potency of antibody-drug conjugates (ADCs) increases with the drug-to-antibody
ratio (DAR); however, ADC plasma clearance also increases with DAR, reducing exposure …

Self-hydrolyzing maleimides improve the stability and pharmacological properties of antibody-drug conjugates

RP Lyon, JR Setter, TD Bovee, SO Doronina… - Nature …, 2014 - nature.com
Many antibody-drug conjugates (ADCs) are unstable in vivo because they are formed from
maleimide-containing components conjugated to reactive thiols. These thiosuccinimide …

The sex industry, alcohol and illicit drugs: implications for the spread of HIV infection

…, MA Plant, DF Peck, J Setters - British Journal of …, 1989 - Wiley Online Library
A review is presented of the association between the sex industry and the use and misuse
of alcohol and illicit drugs. It is concluded that both the latter are associated with “high risk“ …

Intracellular released payload influences potency and bystander-killing effects of antibody-drug conjugates in preclinical models

…, M Jonas, X Zhang, JB Miyamoto, JR Setter… - Cancer research, 2016 - AACR
Antibody-drug conjugates (ADC) comprise targeting antibodies armed with potent small-molecule
payloads. ADCs demonstrate specific cell killing in clinic, but the basis of their …

Interstellar: Using halide's scheduling language to analyze dnn accelerators

X Yang, M Gao, Q Liu, J Setter, J Pu, A Nayak… - Proceedings of the …, 2020 - dl.acm.org
We show that DNN accelerator micro-architectures and their program mappings represent
specific choices of loop order and hardware parallelism for computing the seven nested loops …

[BOOK][B] Hong Kong English

J Setter - 2010 - books.google.com
… for syllables to end with clusters of more than two consonants; Setter (2008a) found none.
Peng and Setter (2000) demonstrated that the process was highly systematic, in that /t/ and /d/ …

Programming heterogeneous systems from an image processing DSL

J Pu, S Bell, X Yang, J Setter, S Richardson… - ACM Transactions on …, 2017 - dl.acm.org
Specialized image processing accelerators are necessary to deliver the performance and
energy efficiency required by important applications in computer vision, computational …

Conjugation of anticancer drugs through endogenous monoclonal antibody cysteine residues

RP Lyon, DL Meyer, JR Setter, PD Senter - Methods in enzymology, 2012 - Elsevier
Many methods have been described for the conjugation of drugs to monoclonal antibodies.
The presence of a discrete number of readily reducible disulfides in the common IgG …

Total shoulder replacement compared with humeral head replacement for the treatment of primary glenohumeral osteoarthritis: a systematic review

CS Radnay, KJ Setter, L Chambers, WN Levine… - Journal of Shoulder and …, 2007 - Elsevier
The optimal choice for the treatment of end-stage primary glenohumeral osteoarthritis remains
controversial, with alternatives including total shoulder replacement (TSR) and humeral …

Greater resistance to footshock punishment in female C57BL/6J mice responding for ethanol

…, KA Fennell, S Bhati, JE Setters… - Alcohol: Clinical and …, 2023 - Wiley Online Library
Background One characteristic of alcohol use disorder is compulsive drinking or drinking
despite negative consequences. When quinine is used to model such aversion‐resistant …