The PI3K/AKT/mTOR (PAM) signaling pathway is a highly conserved signal transduction
network in eukaryotic cells that promotes cell survival, cell growth, and cell cycle progression. …

Background Previous studies have indicated coronavirus disease 2019 (COVID-19) patients
with cancer have a high fatality rate. Methods We conducted a systematic review of studies …

Background We conducted a meta-analysis in nonmetastatic breast cancer patients treated
by neoadjuvant chemotherapy (NCT) to assess the clinical validity of circulating tumor cell (…

Given the scale and rapid spread of the 2019 novel coronavirus (2019-nCoV) acute respiratory
disease, there is an immediate need for medicines that can help before a vaccine can be …

The Lancet, 3 we described how BenevolentAI’s proprietary artificial intelligence (AI)-derived
knowledge graph, 4 queried by a suite of algorithms, enabled identification of a target and …

Background We aimed to assess the clinical validity of circulating tumour cell (CTC) quantification
for prognostication of patients with metastatic breast cancer by undertaking a pooled …

Baricitinib is an oral Janus kinase ( JAK )1/ JAK 2 inhibitor approved for the treatment of
rheumatoid arthritis ( RA ) that was independently predicted, using artificial intelligence ( AI ) …

… J Natl Cancer Inst 92:1823-1830, 2000 5. Herida M, Mary-Krause M, Kaphan R, et al:
Incidence of non-AIDS-defining cancers before and during the highly active antiretroviral …

Purpose: Up to 30% of patients with breast cancer relapse after primary treatment. There
are no sensitive and reliable tests to monitor these patients and detect distant metastases …

Following estrogenic activation, the estrogen receptor-α (ERα) directly regulates the
transcription of target genes via DNA binding. MicroRNAs (miRNAs) modulated by ERα have the …