What type of general practice do patients prefer? Exploration of practice characteristics influencing patient satisfaction.

R Baker, J Streatfield - British Journal of General Practice, 1995 - bjgp.org
… R Baker and J Streatfield … R Baker and J Streatfield … Chambers R, Belcher J. Work
patterns ofgeneral practitioners before and after the introduction of the 1990 contract. Br …

[HTML][HTML] Medical molecular farming: production of antibodies, biopharmaceuticals and edible vaccines in plants

H Daniell, SJ Streatfield, K Wycoff - Trends in plant science, 2001 - cell.com
The use of plants for medicinal purposes dates back thousands of years but genetic engineering
of plants to produce desired biopharmaceuticals is much more recent. As the demand …

Virus-like particles as a highly efficient vaccine platform: diversity of targets and production systems and advances in clinical development

N Kushnir, SJ Streatfield, V Yusibov - Vaccine, 2012 - Elsevier
Virus-like particles (VLPs) are a class of subunit vaccines that differentiate themselves from
soluble recombinant antigens by stronger protective immunogenicity associated with the VLP …

Plant-made vaccine antigens and biopharmaceuticals

H Daniell, ND Singh, H Mason, SJ Streatfield - Trends in plant science, 2009 - cell.com
Plant cells are ideal bioreactors for the production and oral delivery of vaccines and
biopharmaceuticals, eliminating the need for expensive fermentation, purification, cold storage, …

Approaches to achieve high‐level heterologous protein production in plants

SJ Streatfield - Plant biotechnology journal, 2007 - Wiley Online Library
Plants offer an alternative to microbial fermentation and animal cell cultures for the production
of recombinant proteins. For protein pharmaceuticals, plant systems are inherently safer …

Plant-based vaccines: unique advantages

SJ Streatfield, JM Jilka, EE Hood, DD Turner… - Vaccine, 2001 - Elsevier
Numerous studies have shown that viral epitopes and subunits of bacterial toxins can be
expressed and correctly processed in transgenic plants. The recombinant proteins induce …

Clinical development of plant-produced recombinant pharmaceuticals: vaccines, antibodies and beyond

V Yusibov, SJ Streatfield, N Kushnir - Human vaccines, 2011 - Taylor & Francis
In the last few years, plants have become an increasingly attractive platform for recombinant
protein production. This builds on two decades of research, starting with transgenic …

The phosphoenolpyruvate/phosphate translocator is required for phenolic metabolism, palisade cell development, and plastid-dependent nuclear gene expression

SJ Streatfield, A Weber, EA Kinsman, RE Häusler… - The Plant …, 1999 - academic.oup.com
The Arabidopsis chlorophyll a/b binding protein (CAB) gene underexpressed 1 (cue1) mutant
underexpresses light-regulated nuclear genes encoding chloroplast-localized proteins. …

Plant-based vaccines

SJ Streatfield, JA Howard - International journal for parasitology, 2003 - Elsevier
Plant systems are reviewed with regard to their ability to express and produce subunit
vaccines. Examples of different types of expression systems producing a variety of vaccine …

A corn-based delivery system for animal vaccines: an oral transmissible gastroenteritis virus vaccine boosts lactogenic immunity in swine

…, JM Jilka, L Kesl, M Welter, JA Howard, SJ Streatfield - Vaccine, 2004 - Elsevier
Recombinant plant expression systems offer a means to produce large quantities of selected
antigens for subunit vaccines. Cereals are particularly well-suited expression vehicles …