Nitric oxide synthase modulates angiogenesis in response to tissue ischemia.

…, M Kearney, D Chen, JF Symes… - The Journal of …, 1998 - Am Soc Clin Investig
… Walsh, and J. Symes. 1996. Clinical evidence of angiogenesis following arterial gene …
Keyt, JM Isner, and JF Symes. 1996. VEGF improves myocardial blood flow but produces EDRF-…

Therapeutic angiogenesis. A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model.

…, LQ Pu, S Bunting, N Ferrara, JF Symes… - The Journal of …, 1994 - Am Soc Clin Investig
… Carpenter, and JF Symes. A persistent hind limb ischemia model in the rabbit. J. Invest.
Surg… J. Wright. The effect of long-term vasodilation on capillary growth and performenace in …

Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb

…, T Asahara, K Rosenfield, S Razvi, K Walsh, JF Symes - The Lancet, 1996 - thelancet.com
… James F Symes … testing of the plasmid, Kathleen Hogan, Dave Cave, and Jay Duker for
evaluating the patient's suitability for arterial gene therapy, and Susan Kelly, patient's advocate. …

Gene Therapy for Myocardial Angiogenesis: Initial Clinical Results With Direct Myocardial Injection of phVEGF165 as Sole Therapy for Myocardial Ischemia

DW Losordo, PR Vale, JF Symes, CH Dunnington… - Circulation, 1998 - Am Heart Assoc
Background—We initiated a phase 1 clinical study to determine the safety and bioactivity of
direct myocardial gene transfer of vascular endothelial growth factor (VEGF) as sole therapy …

Synergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo

…, S Takeshita, S Bunting, N Ferrara, JF Symes… - Circulation, 1995 - Am Heart Assoc
Background Recent studies have suggested that vascular endothelial growth factor (VEGF)
and basic fibroblast growth factor (bFGF) may have synergistic effects on the induction of …

Responding mindfully to unpleasant thoughts and images: Reliability and validity of the Southampton mindfulness questionnaire (SMQ)

P Chadwick, M Hember, J Symes… - British Journal of …, 2008 - Wiley Online Library
Objective To assess the reliability and validity of the Southampton mindfulness questionnaire
(SMQ), a 16‐item measure of mindful awareness of distressing thoughts and images. …

Local delivery of vascular endothelial growth factor accelerates reendothelialization and attenuates intimal hyperplasia in balloon-injured rat carotid artery

…, S Rossow, S Bunting, N Ferrara, JF Symes… - Circulation, 1995 - Am Heart Assoc
Background Most strategies designed to reduce restenosis by the use of pharmacological
or biological reagents involve direct inhibition of vascular smooth muscle cell (SMC) …

[HTML][HTML] Treatment of thromboangiitis obliterans (Buerger's disease) by intramuscular gene transfer of vascular endothelial growth factor: preliminary clinical results

…, R Blair, O Manor, S Razvi, JF Symes - Journal of vascular …, 1998 - Elsevier
… Dr Symes and his colleagues ought to be congratulated on being in the forefront in studying
this important and promising molecule … I have the following questions for Dr Symes. …

Autologous mesenchymal stem cells produce concordant improvements in regional function, tissue perfusion, and fibrotic burden when administered to patients …

…, S Pham, J Symes, JP Zambrano, J Fishman… - Circulation …, 2014 - Am Heart Assoc
Rationale: Although accumulating data support the efficacy of intramyocardial cell-based
therapy to improve left ventricular (LV) function in patients with chronic ischemic …

Direct intramuscular gene transfer of naked DNA encoding vascular endothelial growth factor augments collateral development and tissue perfusion

…, ST Rossow, J Passeri, JR Horowitz, JF Symes… - Circulation, 1996 - Am Heart Assoc
Background Striated muscle has been shown to be capable of taking up and expressing
foreign genes transferred in the form of naked plasmid DNA, although typically with a low level …