Neonatal acute kidney injury

DT Selewski, JR Charlton, JG Jetton, R Guillet… - …, 2015 - publications.aap.org
In recent years, there have been significant advancements in our understanding of acute
kidney injury (AKI) and its impact on outcomes across medicine. Research based on single-…

A basic science view of acute kidney injury biomarkers

JR Charlton, D Portilla, MD Okusa - Nephrology Dialysis …, 2014 - academic.oup.com
Over the last decade, significant progress has been made in the identification and validation
of novel biomarkers as well as refinements in the use of serum creatinine as a marker of …

Short-term gestation, long-term risk: prematurity and chronic kidney disease

JB Carmody, JR Charlton - Pediatrics, 2013 - publications.aap.org
… Dr Carmody participated in the research drafting and editing of the manuscript; Dr Charlton
formulated the study concept and participated in the research, drafting and editing of the …

Incidence and outcomes of neonatal acute kidney injury (AWAKEN): a multicentre, multinational, observational cohort study

…, M DeFreitas, S Duara, JR Charlton… - The lancet child & …, 2017 - thelancet.com
Background Findings from single-centre studies suggest that neonatal acute kidney injury (AKI)
is associated with poor outcomes. However, because of the small sample size of those …

Recognition and reporting of AKI in very low birth weight infants

…, JR Swanson, ET Rhone, JR Charlton - Clinical Journal of the …, 2014 - journals.lww.com
Results AKI occurred in 39.8% of 455 infants; 75 (16.5%) infants experienced multiple
episodes of AKI, and 8 (2%) infants were discharged with an abnormal last creatinine. Updated …

Some international comparisons of mortality amenable to medical intervention.

JR Charlton, R Velez - Br Med J (Clin Res Ed), 1986 - bmj.com
A series of outcome indicators was proposed for assessing the curative aspects of health
care using several diseases for which evidence suggested that death was largely avoidable …

Consensus-based recommendations on priority activities to address acute kidney injury in children: a modified Delphi consensus statement

…, PD Brophy, R Chanchlani, JR Charlton… - JAMA network …, 2022 - jamanetwork.com
Importance Increasing evidence indicates that acute kidney injury (AKI) occurs frequently in
children and young adults and is associated with poor short-term and long-term outcomes. …

Nephrotoxic medication exposure in very low birth weight infants

…, JB Carmody, JR Swanson, JR Charlton - The Journal of …, 2014 - Taylor & Francis
Objective: To quantify exposure to potentially nephrotoxic medications among very low birth
weight (VLBW) infants and determine the relationship of nephrotoxic medication exposure to …

Advances in neonatal acute kidney injury

MC Starr, JR Charlton, R Guillet, K Reidy… - …, 2021 - publications.aap.org
In this state-of-the-art review, we highlight the major advances over the last 5 years in neonatal
acute kidney injury (AKI). Large multicenter studies reveal that neonatal AKI is common …

Incidence and risk factors of early onset neonatal AKI

JR Charlton, L Boohaker, D Askenazi… - Clinical journal of the …, 2019 - journals.lww.com
Results Twenty-one percent (449 of 2110) experienced early AKI. Early AKI was associated
with higher risk of death (adjusted odds ratio, 2.8; 95% confidence interval, 1.7 to 4.7) and …