Mechanisms of aluminum-induced neurodegeneration in animals: Implications for Alzheimer's disease

J Savory, MM Herman, O Ghribi - Journal of Alzheimer's …, 2006 - content.iospress.com
For four decades the controversial question concerning a possible role for aluminum
neurotoxicity in contributing to the pathogenesis of Alzheimer's disease has been debated, and …

Clinical and environmental aspects of arsenic toxicity

…, RF McCurdy, J Savory - CRC Critical Reviews in …, 1986 - Taylor & Francis
Arsenic (As) is a metalloid belonging to the group of V (A) elements (N, P, As, Sb, and Bi). In
nature, it can exist in three possible oxidation states: the metalloid (0), the trivalent (-3 or+ 3), …

Intracellular mechanisms underlying aluminum-induced apoptosis in rabbit brain

J Savory, MM Herman, O Ghribi - Journal of inorganic biochemistry, 2003 - Elsevier
Loss of neurons is a hallmark of neurodegenerative disorders and there is increasing evidence
suggesting that apoptosis is a key mechanism by which neurons die in these diseases. …

Evaluation of nine automated high-sensitivity C-reactive protein methods: implications for clinical and epidemiological applications. Part 2

…, G Farrow, M Cooper-Anderson, J Savory… - Clinical …, 2001 - academic.oup.com
Background: C-Reactive protein (CRP) can provide prognostic information about risk of future
coronary events in apparently healthy subjects. This application requires higher sensitivity …

Aluminium poisoning: dialysis encephalopathy, osteomalacia, and anaemia

MR Wills, J Savory - The Lancet, 1983 - Elsevier
Occasional Survey Page 1 29 forgiven for regarding the whole issue as rhetorical, an attempt
to retain an ugly past by sentimentalising it. If we ask the patients, we find that continuity is …

The significance of environmental factors in the etiology of Alzheimer's disease

…, A Campbell, RF Itzhaki, J Savory - Journal of Alzheimer's …, 2002 - content.iospress.com
The proposition that environmental agents, such as diet, aluminum, and viruses, are as
important as genetic factors in the etiology of Alzheimer's disease (AD) was advanced by the …

Breakdown of timber by ascomycetes and fungi imperfecti

JG Savory - Annals of Applied Biology, 1954 - Wiley Online Library
Soft rot of wood is caused by certain species of Ascomycetes and Fungi Imperfecti The fungal
hyphae typically run spirally in the central zone of the secondary xylem walls, where they …

Status and future concerns of clinical and environmental aluminum toxicology

TP Flaten, AC Alfrey, JD Birchall, J Savory… - Journal of Toxicology …, 1996 - Taylor & Francis
A wide range of toxic effects of aluminum (Al) have been demonstrated in plants and aquatic
animals in nature, in experimental animals by several routes of exposure, and under …

GDNF protects against aluminum-induced apoptosis in rabbits by upregulating Bcl-2 and Bcl-XL and inhibiting mitochondrial Bax translocation

…, MM Herman, MS Forbes, DA DeWitt, J Savory - Neurobiology of …, 2001 - Elsevier
Direct (intracisternal) injection of aluminum complexes into rabbit brain results in a number
of similarities with the neuropathological and biochemical changes observed in Alzheimer's …

Aluminum and chronic renal failure: sources, absorption, transport, and toxicity

MR Wills, J Savory - Critical reviews in clinical laboratory sciences, 1989 - Taylor & Francis
During the past decade, it has been established that aluminum accumulates in the tissues of
some patients with chronic renal failure. It has also been established that the accumulation …