[HTML][HTML] Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease
CC Bell, DFG Hendriks, SML Moro, E Ellis, J Walsh… - Scientific reports, 2016 - nature.com
Liver biology and function, drug-induced liver injury (DILI) and liver diseases are difficult to
study using current in vitro models such as primary human hepatocyte (PHH) monolayer …
study using current in vitro models such as primary human hepatocyte (PHH) monolayer …
[HTML][HTML] Cytosponge-trefoil factor 3 versus usual care to identify Barrett's oesophagus in a primary care setting: a multicentre, pragmatic, randomised controlled trial
Background Treatment of dysplastic Barrett's oesophagus prevents progression to
adenocarcinoma; however, the optimal diagnostic strategy for Barrett's oesophagus is unclear. The …
adenocarcinoma; however, the optimal diagnostic strategy for Barrett's oesophagus is unclear. The …
Stacking-sequence optimization for buckling of laminated plates by integer programming
RT Haftka, JL Walsh - AIAA journal, 1992 - arc.aiaa.org
Integer-programming formulations for the design of symmetric and balanced laminated plates
under biaxial compression are presented. Both maximization of buckling load for a given …
under biaxial compression are presented. Both maximization of buckling load for a given …
[HTML][HTML] Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver
NR Kitteringham, A Abdullah, J Walsh, L Randle… - Journal of …, 2010 - Elsevier
The transcription factor Nrf2 regulates expression of multiple cellular defence proteins
through the antioxidant response element (ARE). Nrf2-deficient mice (Nrf2 − / − ) are highly …
through the antioxidant response element (ARE). Nrf2-deficient mice (Nrf2 − / − ) are highly …
[HTML][HTML] Diagnosis and management of non-IgE-mediated cow's milk allergy in infancy-a UK primary care practical guide
C Venter, T Brown, N Shah, J Walsh, AT Fox - Clinical and translational …, 2013 - Springer
The UK NICE guideline on the Diagnosis and Assessment of Food Allergy in Children and
Young People was published in 2011, highlighting the important role of primary care …
Young People was published in 2011, highlighting the important role of primary care …
Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice
…, C Goldring, N Kitteringham, J Walsh… - Science translational …, 2015 - science.org
Resveratrol is widely promoted as a potential cancer chemopreventive agent, but a lack of
information on the optimal dose prohibits rationally designed trials to assess efficacy. To …
information on the optimal dose prohibits rationally designed trials to assess efficacy. To …
[HTML][HTML] Better recognition, diagnosis and management of non-IgE-mediated cow's milk allergy in infancy: iMAP—an international interpretation of the MAP (Milk …
C Venter, T Brown, R Meyer, J Walsh, N Shah… - Clinical and …, 2017 - Springer
Cow’s milk allergy (CMA) is one of the most common presentations of food allergy seen in
early childhood. It is also one of the most complex food allergies, being implicated in IgE-…
early childhood. It is also one of the most complex food allergies, being implicated in IgE-…
A comparison of coping strategies used by parents of children with disabilities and parents of children without disabilities
A Paster, D Brandwein, J Walsh - Research in developmental disabilities, 2009 - Elsevier
The purpose of this study was to determine whether coping strategies differ in parents of
children with disabilities and parents of children without disabilities. Participants consisted of …
children with disabilities and parents of children without disabilities. Participants consisted of …
[HTML][HTML] Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile
JA Heslop, C Rowe, J Walsh, R Sison-Young… - Archives of …, 2017 - Springer
The application of primary human hepatocytes following isolation from human tissue is well
accepted to be compromised by the process of dedifferentiation. This phenomenon reduces …
accepted to be compromised by the process of dedifferentiation. This phenomenon reduces …
Differentiating milk allergy (IgE and non-IgE mediated) from lactose intolerance: understanding the underlying mechanisms and presentations
J Walsh, R Meyer, N Shah, J Quekett, AT Fox - British Journal of General …, 2016 - bjgp.org
Children with food allergy and, in particular, infants with suspected adverse reactions to cow’s
milk, commonly present to primary care. It is thought that 6–8% of children aged< 3 years …
milk, commonly present to primary care. It is thought that 6–8% of children aged< 3 years …