[HTML][HTML] Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South …

…, JR Barrett, J Barrett, L Bates, A Batten, K Beadon… - The Lancet, 2021 - thelancet.com
Background A safe and efficacious vaccine against severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), if deployed with high coverage, could contribute to the control of …

[HTML][HTML] Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled …

…, E Barnes, J Barrett, L Bates, A Batten, K Beadon… - The Lancet, 2020 - thelancet.com
Background The pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
might be curtailed by vaccination. We assessed the safety, reactogenicity, and …

[HTML][HTML] Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind …

…, JR Barrett, K Barrett, L Bates, A Batten, K Beadon… - The Lancet, 2020 - thelancet.com
Background Older adults (aged ≥70 years) are at increased risk of severe disease and
death if they develop COVID-19 and are therefore a priority for immunisation should an …

[HTML][HTML] Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a …

…, J Barrett, K Barrett, L Bates, A Batten, K Beadon… - The Lancet, 2021 - thelancet.com
Background The ChAdOx1 nCoV-19 (AZD1222) vaccine has been approved for emergency
use by the UK regulatory authority, Medicines and Healthcare products Regulatory Agency, …

[HTML][HTML] Reactogenicity and immunogenicity after a late second dose or a third dose of ChAdOx1 nCoV-19 in the UK: a substudy of two randomised controlled trials …

…, M Baker, P Baker, JR Barrett, L Bates, K Beadon… - The Lancet, 2021 - thelancet.com
Background COVID-19 vaccine supply shortages are causing concerns about compromised
immunity in some countries as the interval between the first and second dose becomes …

Effect of amoxicillin dose and treatment duration on the need for antibiotic re-treatment in children with community-acquired pneumonia: the CAP-IT randomized …

…, S Segal, S Beer, MJG Garcia, D Georgiou, K Beadon… - Jama, 2021 - jamanetwork.com
Importance The optimal dose and duration of oral amoxicillin for children with community-acquired
pneumonia (CAP) are unclear. Objective To determine whether lower-dose …

Effect of a sedation and ventilator liberation protocol vs usual care on duration of invasive mechanical ventilation in pediatric intensive care units: a randomized clinical …

…, Y Leonard, H Vander-Johnson, D O'Shea, K Beadon… - Jama, 2021 - jamanetwork.com
Importance There is limited evidence on the optimal strategy for liberating infants and
children from invasive mechanical ventilation in the pediatric intensive care unit. Objective To …

Determinants of influenza and pertussis vaccination uptake in pregnancy: a multicenter questionnaire study of pregnant women and healthcare professionals

…, J Metz, E Kilich, R MacLeod, K Beadon… - The Pediatric …, 2019 - journals.lww.com
Methods: Separate questionnaires for pregnant women and HCPs were distributed within 4
national health service (NHS) trusts in South England (July 2017 to January 2018). Results: …

Attitudes of pregnant women and healthcare professionals toward clinical trials and routine implementation of antenatal vaccination against respiratory syncytial virus …

…, J Metz, E Kilich, R MacLeod, K Beadon… - The Pediatric …, 2019 - journals.lww.com
Methods: Separate questionnaires for pregnant women and HCPs were distributed within 4
hospitals in South England (July 2017–January 2018). Results: Responses from 314 …

[HTML][HTML] Conservative versus liberal oxygenation targets in critically ill children (Oxy-PICU): a UK multicentre, open, parallel-group, randomised clinical trial

…, E Beech, II Manjra, SL Hulme, A Sarfatti, K Beadon… - The Lancet, 2024 - thelancet.com
Background The optimal target for systemic oxygenation in critically ill children is unknown.
Liberal oxygenation is widely practiced, but has been associated with harm in paediatric …