Background The objective of this review is to evaluate the efficacy of Pulsed Radiofrequency
(PRF) treatment in chronic pain management in randomized clinical trials (RCTs) and well-…

Inflammatory substances play a part in the modu-lation of pain by interfering with nociceptive
transduction, conduction, and transmission. This modulation may result from alteration of …

Background One of the objectives of medicine is to relieve patients' suffering. As a consequence,
it is important to understand patients' perspectives of suffering and their ability to cope. …

Background According to the World Health Organization (WHO) definition, palliative care
should be initiated in an early phase and not be restricted to terminal care. In the literature, no …

Objective: The aim of this study was to establish the relationship between postoperative pain
and 30-day postoperative complications. Background: Only scarce data are available on …

Background Clinical experience teaches us that patients are willing to accept postoperative
pain, despite high pain intensity scores. Nevertheless, relationships between pain scores …

Background Being involved in caring for family members during illness is part of the Indonesian
culture, even during hospitalization. It is unknown which factors influence the quality of …

Background Despite existing guidelines to assess and manage pain, the management of
cancer-related pain is often suboptimal with patients often being undertreated. Inadequate pain …

Background Hyperalgesia is a well recognized hallmark of disease. Pro-inflammatory cytokines
have been suggested to be mainly responsible, but human data are scarce. Changes in …

Background: Euthanasia has been legally performed in the Netherlands since 2002. Respect
for patient’s autonomy is the underpinning ethical principal. However, patients have no …