[HTML][HTML] Epidemiology of Alzheimer's disease and other forms of dementia in China, 1990–2010: a systematic review and analysis
Background China is increasingly facing the challenge of control of the growing burden of
non-communicable diseases. We assessed the epidemiology of Alzheimer's disease and …
non-communicable diseases. We assessed the epidemiology of Alzheimer's disease and …
Promising strategies for the prevention of dementia
LE Middleton, K Yaffe - Archives of neurology, 2009 - jamanetwork.com
… L Physical activity and enhanced fitness to improve cognitive function in older people
without known cognitive impairment [update of: Cochrane Database Syst Rev. 2008;(2):CD005381]…
without known cognitive impairment [update of: Cochrane Database Syst Rev. 2008;(2):CD005381]…
Systematic evaluation of the associations between environmental risk factors and dementia: an umbrella review of systematic reviews and meta-analyses
Introduction Dementia is a heterogeneous neurodegenerative disease, whose etiology
results from a complex interplay between environmental and genetic factors. Methods We …
results from a complex interplay between environmental and genetic factors. Methods We …
Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Smoking is a leading global cause of disease and mortality 1 . We established the Oxford-GlaxoSmithKline
study (Ox-GSK) to perform a genome-wide meta-analysis of SNP association …
study (Ox-GSK) to perform a genome-wide meta-analysis of SNP association …
Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism
…, GM Halliday, LT Middleton… - Proceedings of the …, 2015 - National Acad Sciences
Prions are proteins that adopt alternative conformations that become self-propagating; the
PrP Sc prion causes the rare human disorder Creutzfeldt–Jakob disease (CJD). We report …
PrP Sc prion causes the rare human disorder Creutzfeldt–Jakob disease (CJD). We report …
[PDF][PDF] Glycyl tRNA synthetase mutations in Charcot-Marie-Tooth disease type 2D and distal spinal muscular atrophy type V
Charcot-Marie-Tooth disease type 2D (CMT2D) and distal spinal muscular atrophy type V (dSMA-V)
are axonal peripheral neuropathies inherited in an autosomal dominant fashion. …
are axonal peripheral neuropathies inherited in an autosomal dominant fashion. …
Mutations in the dystrophin-associated protein γ-sarcoglycan in chromosome 13 muscular dystrophy
…, E Gussoni, PH Denton, T Kyriakides, L Middleton… - Science, 1995 - science.org
… Kyriakides and L. Middleton,Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.
F. Hentati and M. … (A) Upper panel: nt 641 to 654 of l,t1 l } | 1 | …
F. Hentati and M. … (A) Upper panel: nt 641 to 654 of l,t1 l } | 1 | …
[PDF][PDF] Mitochondrial polymorphisms significantly reduce the risk of Parkinson disease
…, JM Stajich, AC McLaurin, LT Middleton… - The American Journal of …, 2003 - cell.com
Mitochondrial (mt) impairment, particularly within complex I of the electron transport system,
has been implicated in the pathogenesis of Parkinson disease (PD). More than half of …
has been implicated in the pathogenesis of Parkinson disease (PD). More than half of …
Treatment of pregnant breast cancer patients and outcomes of children exposed to chemotherapy in utero
…, PH Johnson, N Gordon, H Kuerer, L Middleton… - Cancer, 2006 - Wiley Online Library
BACKGROUND As women in the US delay childbearing, it has been hypothesized that the
incidence of breast cancer diagnosed during pregnancy will increase. There are very little …
incidence of breast cancer diagnosed during pregnancy will increase. There are very little …
Prognostic value of pathologic complete response after primary chemotherapy in relation to hormone receptor status and other factors
Purpose To evaluate whether hormonal receptor (HR) status can influence the prognostic
significance of pathologic complete response (pCR). Patients and Methods This retrospective …
significance of pathologic complete response (pCR). Patients and Methods This retrospective …