User profiles for L. Smeeth

Liam Smeeth

London School of Hygiene and Tropical Medicine
Verified email at lshtm.ac.uk
Cited by 172117

[HTML][HTML] Interpretation of the evidence for the efficacy and safety of statin therapy

…, P Sandercock, K Schulz, P Sever, J Simes, L Smeeth… - The Lancet, 2016 - thelancet.com
… ) by about one-quarter for each mmol/L reduction in LDL cholesterol during each year (after
the … For example, lowering LDL cholesterol by 2 mmol/L (77 mg/dL) with an effective low-cost …

Validation and validity of diagnoses in the General Practice Research Database: a systematic review

…, SL Thomas, WM Schoonen, L Smeeth… - British journal of …, 2010 - Wiley Online Library
AIMS To investigate the range of methods used to validate diagnoses in the General Practice
Research Database (GPRD), to summarize findings and to assess the quality of these …

Effect of inhibitors of the renin-angiotensin system and other antihypertensive drugs on renal outcomes: systematic review and meta-analysis

…, W Chua, S Loukogeorgakis, P Vallance, L Smeeth… - The lancet, 2005 - thelancet.com
L Smeeth helped with the protocol design and statistical analysis. AD Hingorani contributed
to the protocol design and data interpretation. RJ MacAllister contributed to the protocol …

[HTML][HTML] Factors associated with COVID-19-related death using OpenSAFELY

…, F Hester, S Harper, R Perera, SJW Evans, L Smeeth… - Nature, 2020 - nature.com
Coronavirus disease 2019 (COVID-19) has rapidly affected mortality worldwide 1 . There is
unprecedented urgency to understand who is most at risk of severe outcomes, and this …

[HTML][HTML] Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19· 1 million participants

…, CK Mondo, HK Neuhauser, J Sundström, L Smeeth… - The Lancet, 2017 - thelancet.com
Background Raised blood pressure is an important risk factor for cardiovascular diseases
and chronic kidney disease. We estimated worldwide trends in mean systolic and mean …

[HTML][HTML] The REporting of studies Conducted using Observational Routinely-collected health Data (RECORD) statement

EI Benchimol, L Smeeth, A Guttmann, K Harron… - PLoS …, 2015 - journals.plos.org
Routinely collected health data, obtained for administrative and clinical purposes without
specific a priori research goals, are increasingly used for research. The rapid evolution and …

Data resource profile: clinical practice research datalink (CPRD)

…, R Mathur, T Van Staa, L Smeeth - International journal …, 2015 - academic.oup.com
The Clinical Practice Research Datalink (CPRD) is an ongoing primary care database of
anonymised medical records from general practitioners, with coverage of over 11.3 million …

[HTML][HTML] Risk of myocardial infarction and stroke after acute infection or vaccination

L Smeeth, SL Thomas, AJ Hall… - … England Journal of …, 2004 - Mass Medical Soc
Background There is evidence that chronic inflammation may promote atherosclerotic disease.
We tested the hypothesis that acute infection and vaccination increase the short-term risk …

[HTML][HTML] Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1· 25 million people

…, IR White, MJ Caulfield, JE Deanfield, L Smeeth… - The Lancet, 2014 - thelancet.com
Background The associations of blood pressure with the different manifestations of incident
cardiovascular disease in a contemporary population have not been compared. In this study, …

[HTML][HTML] Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5· 24 million UK adults

…, H Forbes, I dos-Santos-Silva, DA Leon, L Smeeth - The Lancet, 2014 - thelancet.com
Background High body-mass index (BMI) predisposes to several site-specific cancers, but a
large-scale systematic and detailed characterisation of patterns of risk across all common …