Rationale: Two forms of the IFN-γ release assay (IFNGRA) to detect tuberculosis infection
are available, but neither has been evaluated in comparable HIV-infected and uninfected …

In March 2020, the United Kingdom Primary Immunodeficiency Network (UKPIN) established
a registry of cases to collate the outcomes of individuals with PID and SID following SARS-…

Objective To compare the effectiveness and acceptability of outpatient polypectomy with
inpatient polypectomy. Design Pragmatic multicentre randomised controlled non-inferiority study…

BACKGROUND Uterine polyps cause abnormal bleeding in women and conventional practice
is to remove them in hospital under general anaesthetic. Advances in technology make it …

Background. Human immunodeficiency virus (HIV)-associated tuberculosis is a major cause
of mortality in Africa. The assay of T cell interferon-γ released in response to antigens of …

Rituximab, an anti-CD20 chimeric antibody, is the first monoclonal agent to be used in the
therapy of cancer. It has been hailed as one of the most important therapeutic developments of …

Objectives The incidence and prevalence of allergies worldwide has been increasing and
allergy services globally are unable to keep up with this increase in demand. This systematic …

Food allergy (FA) is a growing issue worldwide. The United Kingdom and United States are
high-income, industrialized countries with reported increases in FA prevalence over the past …

Background Covid-19 is a novel disease caused by the severe acute respiratory coronavirus
(SARS-CoV2). We discuss a gentleman who presented with an atraumatic rupture of the …

Background Comprehensive national assessments of paediatric allergy services are rarely
undertaken, and have never been undertaken in the United Kingdom. A 2006 survey …