Background Most randomized trials of treatment for asthma study highly selected patients
under idealized conditions. Methods We conducted two parallel, multicenter, pragmatic trials to …

Objectives To determine the proportion of hip fracture patients who experience long-term
disability and to re-estimate the resulting burden of disease associated with hip fractures in …

BACKGROUND: Long-term randomized trials comparing asthma outcomes between
inhaled corticosteroids in real-world populations are lacking. As such, rigorously conducted …

Background Hepatitis E virus (HEV) is the most common acute viral hepatitis in Scotland.
Little is known about the burden of morbidity and mortality, which can be high in chronic liver …

Background: Patient preference is an important factor when choosing an inhaler device for
asthma or chronic obstructive pulmonary disease (COPD). Aims: To identify characteristics of …

Background The incidence of self-harm in young people in primary care is increasing dramatically,
and many young people who self-harm visit their GP surgery as a first point of contact …

Purpose: To evaluate and compare real world cost-effectiveness of inhaled corticosteroids (ICS)
administered by metered dose inhaler (MDI), breath-actuated MDI (BAI), or dry powder …

Self-harm is increasingly common in adolescence, with reported prevalence rates in the UK
varying from 68% 1 to 10%. 2 Though frequently low risk and transient, in some young …

… Linda Kemp has no conflict of interest to declare. Erika Sims has worked on projects
funded by Schering Plough, Merck & Co., Inc., and Teva, and has received funding to attend …

Objectives: To examine patients’ perspectives regarding long-term vitamin K antagonist (VKA)
therapy and the potential transition to new oral anticoagulants (NOACs) such as …