User profiles for M J Farthing

Michael Farthing

Prof of Medicine, University of Sussex
Verified email at sussex.ac.uk
Cited by 25696

Inflammation in ileal reservoirs:'pouchitis'.

MV Madden, MJ Farthing, RJ Nicholls - Gut, 1990 - ncbi.nlm.nih.gov
Unlike conventional ileostomies, ileal faecal reservoirs often become inflamed. The first
reservoirs were continent ileostomies and follow up studies soon showed histological features of …

Abnormal immunoreactivity of the E-cadherin-catenin complex in gastric carcinoma: relationship with patient survival

…, S Poole, P Browne, M Pignatelli, MJ Farthing - Gastroenterology, 1997 - Elsevier
BACKGROUND & AIMS: The E-cadherin-catenin complex plays a critical role in the maintenance
of normal tissue architecture. Mutation of any of its components is believed to result in …

K-ras mutations are found in DNA extracted from the plasma of patients with colorectal cancer

…, XQ Chen, M Stroun, HE Mulcahy, MJ Farthing - Gastroenterology, 1997 - Elsevier
BACKGROUND & AIMS: Circulating DNA can be isolated from the plasma of healthy subjects
and from patients with cancer. The aim of this study was to detect K-ras mutations in DNA …

A prospective study of K-ras mutations in the plasma of pancreatic cancer patients.

…, P Anker, EM Alstead, A Ballinger, MJ Farthing… - Clinical cancer research …, 1998 - AACR
K-ras mutations are frequently found in primary pancreatic adenocarcinomas. In this prospective
study, we looked for K-ras mutations in the plasma of patients with pancreatic cancer. …

Sensibility of the rectum to distension and the anorectal distension reflex in ulcerative colitis.

MJ Farthing, JE Lennard-Jones - Gut, 1978 - gut.bmj.com
The maximum volume of air tolerated within a rectal balloon was less in colitic patients than
in normal subjects (P less than 0.001). Smaller volumes were tolerated by patients with a …

Intestinal transit in anxiety and depression.

DA Gorard, JE Gomborone, GW Libby, MJ Farthing - Gut, 1996 - gut.bmj.com
BACKGROUND: Patients with anxiety and depression often have bowel symptoms. Until
now, studies investigating a link between altered bowel habit and psychological illness have …

Initial response and subsequent course of Crohn's disease treated with elemental diet or prednisolone.

…, KR Palmer, RG Rees, ML Clark, MJ Farthing… - Gut, 1993 - gut.bmj.com
Elemental diet is as effective as corticosteroids in the treatment of previously untreated
Crohn's disease. It is unclear whether a poor nutritional state is a prerequisite for efficacy of …

Oral salt supplements to compensate for jejunostomy losses: comparison of sodium chloride capsules, glucose electrolyte solution, and glucose polymer electrolyte …

…, JE Lennard-Jones, ER Walker, MJ Farthing - Gut, 1992 - gut.bmj.com
Six patients with jejunostomies and residual jejunal lengths of 105 to 250 cm took the same
food and water each day for eight study days. In random order, three methods of salt …

Ambulatory small intestinal motility in'diarrhoea'predominant irritable bowel syndrome.

DA Gorard, GW Libby, MJ Farthing - Gut, 1994 - gut.bmj.com
Dysmotility of the duodenum and proximal jejunum has been reported in patients with
irritable bowel syndrome. This study extended these findings by recording fasting ambulatory …

Diagnostic efficiency of an ultrarapid endoscopy room test for Helicobacter pylori.

…, RS Cook, IG Harrison, S Tabaqchali, MJ Farthing - Gut, 1991 - gut.bmj.com
There are several reliable methods for detecting Helicobacter pylori but all have as a major
disadvantage the time required to yield a definitive result. We have modified the standard …