Physiological adaptations to low‐volume, high‐intensity interval training in health and disease
Exercise training is a clinically proven, cost‐effective, primary intervention that delays and in
many cases prevents the health burdens associated with many chronic diseases. However, …
many cases prevents the health burdens associated with many chronic diseases. However, …
A modern view of phenylalanine ammonia lyase
MJ MacDonald, GB D'Cunha - Biochemistry and Cell Biology, 2007 - cdnsciencepub.com
Phenylalanine ammonia lyase (PAL; EC4.3.1.5), which catalyses the biotransformation of l-phenylalanine
to trans-cinnamic acid and ammonia, was first described in 1961 by Koukol …
to trans-cinnamic acid and ammonia, was first described in 1961 by Koukol …
Molecular genetics: unmasking polyglutamine triggers in neurodegenerative disease
JF Gusella, ME MacDonald - Nature Reviews Neuroscience, 2000 - nature.com
Two decades ago, molecular genetic analysis provided a new approach for defining the roots
of inherited disorders. This strategy has proved particularly powerful because, with only a …
of inherited disorders. This strategy has proved particularly powerful because, with only a …
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
ME MacDonald, CM Ambrose, MP Duyao, RH Myers… - Cell, 1993 - cell.com
The Huntington's disease (HD) gene has been mapped in 4p16.3 but has eluded identification.
We have used haplotype analysis of linkage disequilibrium to spotlight a small segment …
We have used haplotype analysis of linkage disequilibrium to spotlight a small segment …
PRISMA extension for scoping reviews (PRISMA-ScR): checklist and explanation
…, S Lewin, CM Godfrey, MT Macdonald… - Annals of internal …, 2018 - acpjournals.org
Scoping reviews, a type of knowledge synthesis, follow a systematic approach to map evidence
on a topic and identify main concepts, theories, sources, and knowledge gaps. Although …
on a topic and identify main concepts, theories, sources, and knowledge gaps. Although …
Treatment of mild hypertension study: final results
…, KH Svendsen, A Leon, B Laing, M McDonald… - Jama, 1993 - jamanetwork.com
… in M-mode echocardiography: results of a survey of echocardiographic measurements. …
Sokolow M, Lyon TP. Ventricular complex in left ventricular hypertrophy as obtained by …
Sokolow M, Lyon TP. Ventricular complex in left ventricular hypertrophy as obtained by …
The lexical nature of syntactic ambiguity resolution.
MC MacDonald, NJ Pearlmutter… - Psychological …, 1994 - psycnet.apa.org
… MacDonald compared self-paced reading times in the disambiguation region (were afraid)
for the two ambiguous conditions with the unambiguous control. Reading times for the biased …
for the two ambiguous conditions with the unambiguous control. Reading times for the biased …
Trinucleotide repeat length instability and age of onset in Huntington's disease
…, J Srinidhi, G Barnes, J Gusella, M MacDonald - Nature …, 1993 - nature.com
The initial observation of an expanded and unstable trinucleotide repeat in the Huntington's
disease gene has now been confirmed and extended in 150 independent Huntington's …
disease gene has now been confirmed and extended in 150 independent Huntington's …
Similar metabolic adaptations during exercise after low volume sprint interval and traditional endurance training in humans
…, M Rakobowchuk, MJ MacDonald… - The Journal of …, 2008 - Wiley Online Library
… mm Tris (pH 7.5), 1 mm EDTA, 1 mm EGTA, 10% glycerol, 1% Triton X-100, 50 mm NaF, 5
mm sodium pyrophosphatase, 1 mm … transfer buffer (37 mm Tris base, 140 mm glycine and 20…
mm sodium pyrophosphatase, 1 mm … transfer buffer (37 mm Tris base, 140 mm glycine and 20…
[HTML][HTML] Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection
…, D Ceradini, SR Martin, R Horuk, ME MacDonald… - Cell, 1996 - cell.com
Rare individuals have been multiply exposed to HIV-1 but remain uninfected. The CD4 + T-cells
of two of these individuals, designated EU2 and EU3, are highly resistant in vitro to the …
of two of these individuals, designated EU2 and EU3, are highly resistant in vitro to the …