Short‐term treatment with proton pump inhibitors, H2‐receptor antagonists and prokinetics for gastro‐oesophageal reflux disease‐like symptoms and endoscopy …

…, PA Bonis, J Lau, ME Numans - Cochrane Database …, 2013 - cochranelibrary.com
Background Approximately 25% of adults regularly experience heartburn, a symptom of
gastro‐oesophageal reflux disease (GORD). Most patients are treated empirically (without …

Non‐pharmacological interventions for somatoform disorders and medically unexplained physical symptoms (MUPS) in adults

…, SS Leone, B Terluin, ME Numans… - Cochrane Database …, 2014 - cochranelibrary.com
Background Medically unexplained physical symptoms (MUPS) are physical symptoms for
which no adequate medical explanation can be found after proper examination. The …

How useful is paracetamol absorption as a marker of gastric emptying? A systematic literature study

M Willems, AO Quartero, ME Numans - Digestive diseases and sciences, 2001 - Springer
… 4), or the study did not concern humans (N … Horowitz M, Collins PJ, Shearman DJC: Disorders
of gastric emptying in humans and the use of radionuclide techniques. Arch Intern Med 145…

Genome-wide association study identifies eight loci associated with blood pressure

…, CS Uiterwaal, YT van der Schouw, ME Numans… - Nature …, 2009 - nature.com
Elevated blood pressure is a common, heritable cause of cardiovascular disease worldwide.
To date, identification of common genetic variants influencing blood pressure has proven …

Short-term treatment with proton-pump inhibitors as a test for gastroesophageal reflux disease: a meta-analysis of diagnostic test characteristics

ME Numans, J Lau, NJ de Wit… - Annals of internal …, 2004 - acpjournals.org
… The systematic review of Numans ME et al. shows that a positive proton pump inhibitors (PPI)
test does not support and a negative one does not exclude the diagnosis of GERD as …

Fruit and vegetable intake and the risk of stomach and oesophagus adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC …

…, FL Büchner, PHM Peeters, ME Numans… - … journal of cancer, 2006 - Wiley Online Library
It is considered that fruit and vegetable (F&V) protect against oesophagus and gastric cancer
(GC). However, 2 recent meta‐analyses suggest that the strength of association on GC …

Meat intake and risk of stomach and esophageal adenocarcinoma within the European Prospective Investigation Into Cancer and Nutrition (EPIC)

…, M Ocke, PHM Peeters, ME Numans… - Journal of the …, 2006 - academic.oup.com
Background: Dietary factors are thought to have an important role in gastric and esophageal
carcinogenesis, but evidence from cohort studies for such a role is lacking. We examined …

Estimating interaction on an additive scale between continuous determinants in a logistic regression model

…, DE Grobbee, ME Numans… - International journal …, 2007 - academic.oup.com
Background To determine the presence of interaction in epidemiologic research, typically a
product term is added to the regression model. In linear regression, the regression coefficient …

Disturbed solid-phase gastric emptying in functional dyspepsia (a meta-analysis)

AO Quarter, NJ De Wit, AC Lodder, ME Numans… - Digestive diseases and …, 1998 - Springer
Functional dyspepsia is a common disorder witha diverse pathophysiological background,
but the role ofmotility disorders in functional dyspepsia remainsunclear. We aimed to quantify …

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption

…, C Mueller, G Navis, ME Numans… - Proceedings of the …, 2011 - National Acad Sciences
… (7–9), few genes regulating alcohol consumption in humans have been described—with the
… We then carried out functional genetic studies in both humans and animal models (Fig. S1). …