Short‐term treatment with proton pump inhibitors, H2‐receptor antagonists and prokinetics for gastro‐oesophageal reflux disease‐like symptoms and endoscopy …
Background Approximately 25% of adults regularly experience heartburn, a symptom of
gastro‐oesophageal reflux disease (GORD). Most patients are treated empirically (without …
gastro‐oesophageal reflux disease (GORD). Most patients are treated empirically (without …
Non‐pharmacological interventions for somatoform disorders and medically unexplained physical symptoms (MUPS) in adults
Background Medically unexplained physical symptoms (MUPS) are physical symptoms for
which no adequate medical explanation can be found after proper examination. The …
which no adequate medical explanation can be found after proper examination. The …
How useful is paracetamol absorption as a marker of gastric emptying? A systematic literature study
M Willems, AO Quartero, ME Numans - Digestive diseases and sciences, 2001 - Springer
… 4), or the study did not concern humans (N … Horowitz M, Collins PJ, Shearman DJC: Disorders
of gastric emptying in humans and the use of radionuclide techniques. Arch Intern Med 145…
of gastric emptying in humans and the use of radionuclide techniques. Arch Intern Med 145…
Genome-wide association study identifies eight loci associated with blood pressure
…, CS Uiterwaal, YT van der Schouw, ME Numans… - Nature …, 2009 - nature.com
Elevated blood pressure is a common, heritable cause of cardiovascular disease worldwide.
To date, identification of common genetic variants influencing blood pressure has proven …
To date, identification of common genetic variants influencing blood pressure has proven …
Short-term treatment with proton-pump inhibitors as a test for gastroesophageal reflux disease: a meta-analysis of diagnostic test characteristics
… The systematic review of Numans ME et al. shows that a positive proton pump inhibitors (PPI)
test does not support and a negative one does not exclude the diagnosis of GERD as …
test does not support and a negative one does not exclude the diagnosis of GERD as …
Fruit and vegetable intake and the risk of stomach and oesophagus adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC …
…, FL Büchner, PHM Peeters, ME Numans… - … journal of cancer, 2006 - Wiley Online Library
It is considered that fruit and vegetable (F&V) protect against oesophagus and gastric cancer
(GC). However, 2 recent meta‐analyses suggest that the strength of association on GC …
(GC). However, 2 recent meta‐analyses suggest that the strength of association on GC …
Meat intake and risk of stomach and esophageal adenocarcinoma within the European Prospective Investigation Into Cancer and Nutrition (EPIC)
…, M Ocke, PHM Peeters, ME Numans… - Journal of the …, 2006 - academic.oup.com
Background: Dietary factors are thought to have an important role in gastric and esophageal
carcinogenesis, but evidence from cohort studies for such a role is lacking. We examined …
carcinogenesis, but evidence from cohort studies for such a role is lacking. We examined …
Estimating interaction on an additive scale between continuous determinants in a logistic regression model
…, DE Grobbee, ME Numans… - International journal …, 2007 - academic.oup.com
Background To determine the presence of interaction in epidemiologic research, typically a
product term is added to the regression model. In linear regression, the regression coefficient …
product term is added to the regression model. In linear regression, the regression coefficient …
Disturbed solid-phase gastric emptying in functional dyspepsia (a meta-analysis)
AO Quarter, NJ De Wit, AC Lodder, ME Numans… - Digestive diseases and …, 1998 - Springer
Functional dyspepsia is a common disorder witha diverse pathophysiological background,
but the role ofmotility disorders in functional dyspepsia remainsunclear. We aimed to quantify …
but the role ofmotility disorders in functional dyspepsia remainsunclear. We aimed to quantify …
Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption
… (7–9), few genes regulating alcohol consumption in humans have been described—with the
… We then carried out functional genetic studies in both humans and animal models (Fig. S1). …
… We then carried out functional genetic studies in both humans and animal models (Fig. S1). …