User profiles for M. Abulafi
 | Muti AbulafiConsultant Colorectal Surgeon, Croydon University Hospital Verified email at nhs.net Cited by 4519 |
[HTML][HTML] Role of the faecal immunochemical test in patients with risk-stratified suspected colorectal cancer symptoms: A systematic review and meta-analysis to inform …
…, M Westwood, J Kleijnen, M Abulafi - The Lancet Regional …, 2022 - thelancet.com
Background The UK National Institute for Health and Care Excellence (NICE), recommended
in 2017 the use of the faecal immunochemical test (FIT) to guide investigations in patients …
in 2017 the use of the faecal immunochemical test (FIT) to guide investigations in patients …
[HTML][HTML] Prognostic importance of MRI-detected extramural venous invasion in rectal cancer: a literature review and systematic meta-analysis
JJ Tan, RV Carten, A Babiker, M Abulafi… - International Journal of …, 2021 - Elsevier
Purpose Extramural venous invasion (EMVI) is recognized as a poor prognostic factor in
rectal cancer. There are well-documented limitations associated with pathology detection of …
rectal cancer. There are well-documented limitations associated with pathology detection of …
Faecal immunochemical test is superior to symptoms in predicting pathology in patients with suspected colorectal cancer symptoms referred on a 2WW pathway: a …
Objective To assess whether a faecal immunochemical test (FIT) could be used to select
patients with suspected colorectal cancer (CRC) symptoms for urgent investigation. Design …
patients with suspected colorectal cancer (CRC) symptoms for urgent investigation. Design …
MRI-diagnosed tumor deposits and EMVI status have superior prognostic accuracy to current clinical TNM staging in rectal cancer
Objective: We aimed to assess whether mrTDs and mrLNMs have different prognostic
implications and compare these to other known prognostic markers. Methods: This was a …
implications and compare these to other known prognostic markers. Methods: This was a …
The rectosigmoid problem
The lack of consensus over the transition point for the end of the sigmoid and beginning of
the rectum is a problem for the colorectal multidisciplinary team. In this review, we survey the …
the rectum is a problem for the colorectal multidisciplinary team. In this review, we survey the …
Faecal immunochemical testing (FIT) in patients with signs or symptoms of suspected colorectal cancer (CRC): a joint guideline from the Association of Coloproctology …
KJ Monahan, MM Davies, M Abulafi, A Banerjea… - Gut, 2022 - gut.bmj.com
Faecal immunochemical testing (FIT) has a high sensitivity for the detection of colorectal
cancer (CRC). In a symptomatic population FIT may identify those patients who require …
cancer (CRC). In a symptomatic population FIT may identify those patients who require …
Prioritisation by FIT to mitigate the impact of delays in the 2-week wait colorectal cancer referral pathway during the COVID-19 pandemic: a UK modelling study
Objective To evaluate the impact of faecal immunochemical testing (FIT) prioritisation to
mitigate the impact of delays in the colorectal cancer (CRC) urgent diagnostic (2-week-wait (…
mitigate the impact of delays in the colorectal cancer (CRC) urgent diagnostic (2-week-wait (…
Whole‐genome methylation analysis of benign and malignant colorectal tumours
…, A Jones, M El‐Bahwary, M Abulafi… - The Journal of …, 2013 - Wiley Online Library
Abstract Changes in DNA methylation, whether hypo‐ or hypermethylation, have been
shown to be associated with the progression of colorectal cancer. Methylation changes …
shown to be associated with the progression of colorectal cancer. Methylation changes …
Adverse features on rectal MRI identify a high-risk group that may benefit from more intensive preoperative staging and treatment
Background Magnetic resonance imaging (MRI) is highly accurate in local staging of rectal
cancer. It can identify features known to be associated with increased risk of metastatic …
cancer. It can identify features known to be associated with increased risk of metastatic …
[HTML][HTML] Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is …
Repair of double strand DNA breaks (DSBs) is pivotal in maintaining normal cell division
and disruption of this system has been shown to be a key factor in carcinogenesis. Loss of …
and disruption of this system has been shown to be a key factor in carcinogenesis. Loss of …