Background It is increasingly acknowledged that ‘acceptability’ should be considered when
designing, evaluating and implementing healthcare interventions. However, the published …

We reviewed the literature on the assessment of acceptability of HIV prevention and treatment
interventions and service delivery strategies. Following PRISMA guidelines, we screened …

Strategies for assembling large, complex genomes have evolved to include a combination of
whole-genome shotgun sequencing and hierarchal map-assisted sequencing 1 , 2 . Whole-…

The International Human Genome Sequencing Consortium (IHGSC) used a hierarchical
mapping and sequencing strategy to construct the working draft of the human genome. This …

A physical map of a genome is an essential guide for navigation, allowing the location of any
gene or other landmark in the chromosomal DNA. We have constructed a physical map of …

Human chromosome 7 has historically received prominent attention in the human genetics
community, primarily related to the search for the cystic fibrosis gene and the frequent …

Background The theoretical framework of acceptability (TFA) was developed in response to
recommendations that acceptability should be assessed in the design, evaluation and …

The non-recombining region of the human Y chromosome (NRY), which comprises 95% of
the chromosome, does not undergo sexual recombination and is present only in males. An …

The human genome is by far the largest genome to be sequenced, and its size and complexity
present many challenges for sequence assembly. The International Human Genome …

The important role of service users in managing their own healthcare is widely recognised.
The advent of person-centred care (Royen et al., 2010) has legitimised the views of people …