The aim of this study was to evaluate which factors are associated with asthma control
experienced by asthma patients. In a cross-sectional study patients aged 16–60 years with mild to …

BACKGROUND: Exposure to allergens plays a role in the development of bronchial
hyperresponsiveness and in the chronic inflammatory response seen in asthmatic patients. House …

Background The efficacy of bed covers that are impermeable to house dust mites has been
disputed. Aim The aim of the present study was to investigate whether the combination of ‘…

Aim: To assess whether exposure to house dust mite (HDM) allergens hampers a tapering off
of inhaled corticosteroid (ICS) dosage in HDM-sensitive asthma patients. Methods: Asthma …

The aim of this study was to evaluate the effect of house dust mite impermeable covers on
asthma-specific health-related quality of life in adult asthmatic patients that were trained in …

To identify candidate genes for intellectual disability, we performed a meta-analysis on
2,637 de novo mutations, identified from the exomes of 2,104 patient–parent trios. Statistical …

Background The causes of intellectual disability remain largely unknown because of
extensive clinical and genetic heterogeneity. Methods We evaluated patients with intellectual …

Intellectual disability (ID) is a highly heterogeneous disorder involving at least 600 genes, yet
a genetic diagnosis remains elusive in ∼35%–40% of individuals with moderate to severe …

Lugtenberg M, De Vries PR, Evertse AJ, Zegers-van Schaick JM, Westert GP, Burgers JS.
Welke barrières ervaren huisartsen bij de toepassing van aanbevelingen uit NHG-…

Micro RNA s (mi RNA ) play a crucial role in the regulation of diverse biological processes
by post‐transcriptional modulation of gene expression. Genetic polymorphisms in mi RNA ‐…