Background Chemotherapy combinations that include an alkylating agent and a platinum
coordination complex have high response rates in women with advanced ovarian cancer. …

Background Vascular endothelial growth factor is a key promoter of angiogenesis and
disease progression in epithelial ovarian cancer. Bevacizumab, a humanized anti–vascular …

Soil biodiversity plays a key role in regulating the processes that underpin the delivery of
ecosystem goods and services in terrestrial ecosystems. Agricultural intensification is known to …

OBJECTIVE: The Gynecologic Oncology Group has divided patients with advanced epithelial
ovarian cancer into those with optimal residual cancer, in which the maximum diameter of …

Inflammatory mediators play a key role in acute pancreatitis and the resultant multiple organ
dysfunction syndrome, which is the primary cause of death in this condition. Recent studies …

Background Data are limited regarding the use of poly(adenosine diphosphate [ADP]–ribose)
polymerase inhibitors, such as veliparib, in combination with chemotherapy followed by …

Purpose To determine if incorporation of an additional cytotoxic agent improves overall
survival (OS) and progression-free survival (PFS) for women with advanced-stage epithelial …

Background. A clinicopathologic evaluation of clinical Stage I and II uterine sarcoma was done
by the Gynecologic Oncology Group from 1979–1988. Methods. After all eligibility criteria …

Importance Germline mutations inBRCA1andBRCA2are relatively common in women with
ovarian, fallopian tube, and peritoneal carcinoma (OC) causing a greatly increased lifetime …

Intensive land use reduces the diversity and abundance of many soil biota, with consequences
for the processes that they govern and the ecosystem services that these processes …