Background The prevalence of coeliac disease (CD) is around 1%, but diagnosis is
challenged by varied presentation and non-specific symptoms and signs. This study aimed to …

Background Updatable estimates of COVID-19 onset, progression, and trajectories underpin
pandemic mitigation efforts. To identify and characterise disease trajectories, we aimed to …

Pathology tests have a unique place in management of chronic diseases. They are used to
guide disease management; assess risk and compliance; and enable early detection of …

Background Prevention of childhood obesity is an international public health priority given
the significant impact of obesity on acute and chronic diseases, general health, development …

Early life adversity (ELA) is associated with a higher risk for diseases in adulthood. Although
the pathophysiological effects of ELA are varied, there may be a unifying role for the …

Importance The current diagnostic pathway for patients with suspected prostate cancer (PCa)
includes prostate biopsy. A large proportion of individuals who undergo biopsy have either …

Early life adversity (ELA) increases the risk for multiple age-related diseases, such as diabetes
type 2 and cardiovascular disease. As prevalence is high, ELA poses a major and global …

Early life adversity (ELA) has been associated with an increased risk for diseases in which
the immune system plays a critical role. The ELA immune phenotype is characterized by …

Background There is growing support for a biopsy avoidant approach to diagnose coeliac
disease in both children and adults, using a serological diagnosis instead. Aims To assess the …

Background Acute respiratory tract infections (RTIs) are the most common reason to seek
medical care, with many patients receiving inappropriate antibiotics. Novel testing approaches …