Objective To assess how pressures from patients on doctors in the consultation contribute to
referral and investigation. Design Observational study nested within a randomised …

Objective To assess the impact of leaflets encouraging patients to raise concerns and to
discuss symptoms or other health related issues in the consultation. Design Randomised …

BACKGROUND: Physical activity is a major modifiable risk factor for cardiovascular disease,
but it is unclear what combination of feasible approaches, using existing resources in …

Objective To assess the effect of brief interventions during the “watchful waiting” period for
hypertension. Design Factorial trial. Setting General practice. Methods 296 patients with blood …

Aims Phosphodiesterase isoenzymes may play an important role in the regulation of airway
calibre and bronchial smooth muscle function. Immunomodulatory actions may also be …

Rhinovirus (HR V) may be the predominant cause of asthma exacerbations in children as
well as adults. Although worsening of existing airway disease is probably mediated by means …

Nurses measured blood pressure by using semiautomated monitors (minimising measurement
bias) and gave structured advice in all groups (minimising placebo effect 1 2). Any bias is …

This thesis addresses two key questions: Do patients who attend a practice, where the Primary
Health Care Team follow the 1993 British Thoracic Society (BTS) guidelines have a better …

Editor—Despite research in tropical medicine being undertaken in countries from low human
development index, authorship and editorial opinion remain with countries from higher …

Biologicals are distinct from small molecule drugs in that they are larger, more structurally
complex agents. While the overall risk is modest, the active protein structure characteristic of …