Background— Extracellular adenosine, generated from extracellular nucleotides via
ectonucleotidases, binds to specific receptors and provides cardioprotection from ischemia and …

Complement activation plays an important role in local and remote tissue injury associated
with gastrointestinal ischemia-reperfusion (GI/R). The role of the classical and lectin …

Invasive pneumococcal infection is an important cause of morbidity and mortality in HIV-1-infected
individuals. B cells play an important role in maintaining serologic memory after …

Mannose-binding lectin (MBL) is present in human serum and plays an important role in
innate immunity by binding to carbohydrate on micro-organisms. Whereas the gp120/gp41 of …

Intestinal ischemia/reperfusion injury (IR) is characterized by intermittent loss of perfusion to
the gut, resulting in dramatic increases in morbidity and mortality. Based on previous studies …

Recent evidence has implicated a role for the MBL-dependent lectin pathway in gastrointestinal
and myocardial ischemia/reperfusion (I/R)-induced injury. However, previous studies …

The heterogeneous disease course of COVID-19 is unpredictable, ranging from mild self-limiting
symptoms to cytokine storms, acute respiratory distress syndrome (ARDS), multi-organ …

Ischemia/reperfusion injury (IRI) of the liver is an important cause of hepatic dysfunction.
Ischemic preconditioning (IP) is associated with adenosine-mediated tissue protection from …

Gastrointestinal ischemia/reperfusion (IR) injury significantly contributes to the morbidity and
mortality of critical illness. In this study, we hypothesized a protective role for extracellular …

BACKGROUND & AIMS: The liver tolerates ischemia/reperfusion (IR) poorly. The discovery
of ischemic preconditioning (IP) has raised hopes that natural pathways could be activated to …