Background Up to 60% of patients with Crohn's disease need intestinal resection within the
first 10 years of diagnosis, and postoperative recurrence is common. We investigated …

Anal fissures are tears of the anal mucosa. They can cause extreme pain (often up to 1–2
hours post-defaecation) and in many cases bleeding. Acute anal fissures are classified as …

Background: Childbirth injuries are common in Uganda. This paper describes our experience
with Vesico-vaginal Fistula repair and aftercare. Methods: Between 1999 and 2003, 341 …

Background & Aims DNA methylation alterations may provide important insights into gene-environment
interaction in cancer, aging, and complex diseases, such as inflammatory bowel …

A long‐term, large‐scale ethnic armed conflict continues in Sri Lanka, where militant separatists
control a northern section of the island. The conflict has resulted in a large population of …

Laparoscopic ventral mesh rectopexy (VMR) has become a popular surgical technique for
treating women with full-thickness rectal prolapse with a low recurrence rate, as demonstrated …

<p>Northern Sri Lanka has been separated by an active front line from the remainder of the
country and has lacked basic facilities, including hospital care, because of the war between …

Introduction: Carcinoembryonic antigen (CEA) is an oncofoetal antigen heterogeneously
expressed by colorectal cancer cells, which may provide a useful target for antibody guided …

Currently there is no documentation in the English-language literature of the effect of
postoperative C. difficile infection on a colorectal anastomosis. We hypothesize that postoperative …

Across the UK, patients are presented with an inequality of access to care resulting from the
patchy nature of services for continence and functional pelvic conditions. Expertise in …